Alex Puttick @ATPutty
PhD’er in Ghorashian Lab at UCL’s Great Ormond Street Institute of Child Health. Researching next-gen CAR-T cell therapy for AML. Opinions are my own. London, England Joined September 2022-
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Long-term success of BCMA-CAR-T in multiple myeloma patients linked to CD4+ T cell-driven cytotoxicity, memory-biased T cell states, reduced exhaustion, and microenvironment effects @Cancer_Cell cell.com/cancer-cell/fu… preview by @NikhilMunshiMD cell.com/cancer-cell/fu…
First proof-of-concept for engineered T cells as a potential treatment for Alzheimer's disease @jonykipnis @boskovic_p @PNASNews @justsaysinmice pnas.org/doi/10.1073/pn…
Engineering T cells (CAR-T) has had marked benefits for cancer and autoimmune disease. But doing that inside the patient's body (in vivo) would make that far more practical and less expensive. cell.com/cell-reports-m…
@NatRevImmunol Guidelines for T cell nomenclature nature.com/articles/s4157… @Masopust_Vezys et al.
James Dewey Watson – who won the Nobel Prize for his role in divining the structure of DNA; was instrumental in initiating and propelling the Human Genome Project; and who became notorious for his history of racist and sexist comments – has died at 97. go.nature.com/4hP5lGP
Engineering T cells with a membrane-tethered version of SLP-76 overcomes antigen-low resistance to CAR T cell therapy @NatureCancer @Majzner_Lab @mcrotiroti @DanaFarber 🇺🇸 nature.com/articles/s4301…
Our new, comprehensive review on CAR T cell persistence is officially published in @CellCellPress @trendscancer. Fantastic work from lead authors @kpmueller1 @JGrenierMDPhD. Link to the full article: cell.com/trends/cancer/…
Our new publication in @NBME on engineering CAR T cells with a secreted anti-PDL1-IL12 fusion for the treatment of solid tumors. Congrats to @JohnPMuradPhD and our collaborators. Thanks to @PCF, @DeptofDefense, and foundations! @uscnorris @cityofhope nature.com/articles/s4155…
@UFHealthCancer @PatrickHwuMD @MoffittNews @UF Oh amazing! Thank you so much for sharing ☺️
CD19 CAR-T coming to IBD $CABA $KYTX $CGEM New N=1 case report from Schett describes clinical / biochemical remission achieved with auto CD19 CAr-T in refractory Ulcerative Colitis Can't find the article anywhere... potentially a bungled embargo? Should be on NEJM soon enough
Durable CAR T persistence is among the great unsolved challenges within our field. But what do we actually mean when we say a CAR T cell is "persistent"? @JGrenierMDPhD, @EvanWeberPhD and I attempt to answer this question in our new review @trendscancer. 1/
Congratulations to @DaniyanMd & team from @MSKCancerCenter on publication of the initial data from AML patients treated with IL-18 secreting CD371 CAR T cells @MSK. ashpublications.org/blood/article-… 3 / 5 patients experienced MRD-negative morphologic leukemia free state.
Our manuscript using single cell RNA sequencing to compare two CD19 CAR T cell products, axi-cel and tisa-cel is online at JITC! @DrFredLocke @MoffittNews jitc.bmj.com/content/13/7/e… . Our findings (thread):
Probably in lab, trying to finish their PhD
I want to know where the 27-32 years olds in SF are hiding, have not met very many
A cancer vaccine that targets lymph nodes has encouraging Phase 1 clinical trial results for potent and durable increased immune response vs KRAS mutation tumors nature.com/articles/s4159… @NatureMedicine
Must read for CAR-T folks. Early data supporting the applicability of in vivo but long term survival still unknown. Synthetic T-cells are weird so will be fascinating to know how in vivo CARs persist relative to ex vivo counterparts. Kudos to the team for this important study 🙏
In vivo BCMA CAR T for relapsed myeloma @TheLancet - 4/4 patients responded - pretty wild stuff! thelancet.com/journals/lance… #mmsm
@Eddie_Cliff @TheLancet Which should make the resulting product more efficacious/persistent etc. this is obviously a v small data set but I’m wondering with in vivo if there’s a higher risk of low persistence as there’s no selectivity in T cell phenotype other than CD3?
@Eddie_Cliff @TheLancet I’m interested to get your thoughts btw on the relative advantage of ex vivo vs in vivo in the selection of T cells we transduce before giving the product to the patient.We’ve come so far with ex vivo manufacturing that we can much more precisely influence T cell phenotype 1/2.
@Eddie_Cliff @TheLancet Wow this is so interesting. Also incredible that the CAR-T field at large have only started debating the idea of in vivo products and before you know it, there’s a published data from a Chinese clinical trial. The speed from conception to execution is quite astonishing.
Megen Wittling @megen_wittling
300 Followers 557 Following MD/PhD student at Emory University 🧬 🧪 🧫 | grad student in @PaulosLab | opinions my own
Rhea @AxIx7vW82aNM9Qq
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Society for Immunothe... @sitcancer
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Yang Zhao @YangZhao102
163 Followers 198 Following T cell engineering & cytokine signaling in the Garcia lab｜Postdoc @Stanford_MCP ｜CRI fellow @CancerResearch | PhD @EPFL
Simone Minnie @simone_minnie
1K Followers 414 Following Assistant Professor @UCSF | Minnie Lab | #Myeloma Research | #Immunotherapy | #ASCT | #CAR-T | Opinions are my own 👩🏻🔬🇦🇺 https://t.co/fUtrCPLQDL
Wansang Cho @ScienceWansang
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Dr. Patrick Hwu @PatrickHwuMD
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Nicola maciocia @nicola_maciocia
138 Followers 325 Following Haematologist | Academic clinical lecturer in CAR-T | Mum of three | @ucl @uclh @NIHR
Gregory Lesinski @LesinskiLab
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Jennifer Trowbridge @TrowbridgeLab
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Satya Prakash Yadav @Satyayadav__
5K Followers 2K Following Director- Pediatric Hematology Oncology & Bone Marrow Transplant, Medanta The Medicity . Chairperson-PHO chapter of IAP @pho_india RT are not endorsement
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Lindsey Draper @Lindsey__Draper
356 Followers 581 Following Physician-scientist at @UCSF focusing on ovarian cancer. Engineering TIL in the @roybal_lab. @parkerici @MountSinaiNYC @theNCI
Christopher Heery MD @ChrisHeery
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tejada @tejada444
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Laurie Menger @LaurieMengerLab
364 Followers 308 Following INSERM tenured scientist ATIP-avenir Institut Gustave Roussy U1015 In vivo genome-wide CRISPR screens for T-cell therapies Lab
Davide Pisu @mtbmeds
2K Followers 2K Following Professor 🥼🎓| Host-pathogen interactions w/ M. tuberculosis 🦠 | Macrophages 🔬 | Infectious diseases 🧫 | Soccer ⚽ & F1 🏎️ enthusiast!
Steven Artandi, MD, P... @SCIDirector
4K Followers 2K Following Stanford University medical oncologist and cancer scientist, and Director of the Stanford Cancer Institute. Follows and retweets are not endorsements.
Enrique Grande @drenriquegrande
13K Followers 9K Following Medical Oncology Department Director at Quironsalud Madrid. Opinions are my own. https://t.co/DrJu4J331O
TheNightTrader @TheNightTrader2
73 Followers 2K Following +20 trading experience...buy-side, sell-side, execution, prop
Nour Shobaki @NourShobaki
342 Followers 1K Following PharmD PhD, Director of Research, Head of The BRITE Lab | PCF Investigator | SITC SPARKY (working with Dr. Carl June) @PennMedicine
May Daher @may_daher
1K Followers 639 Following Physician scientist at MD Anderson Cancer Center with focus on cellular therapy, gene editing and immunometabolism to treat cancer patients. Tweets are my own.
SoniaGuedan @GuedanS
808 Followers 463 Following Cancer immunologist at IDIBAPS-HCB. Passionate about developing CAR-T cells for cancer. Feminist who believes in the power of science and social change.
Hind Rafei @HindRafei
3K Followers 4K Following Physician-scientist at MD Anderson Cancer Center investigating cellular immunotherapy for cancer with a focus on metabolic-epigenetic crosstalk in the TME.
Haidong Dong @hd_DongMDPhD
303 Followers 336 Following #TumorImmunology/immunotherapy. To identify and produce resilient cytotoxic T cells for cancer immunotherapy.
Anand Bhagwat, MD, Ph... @anandbmdphd
252 Followers 236 Following Oncologist @ChildrensPhila. In @GillSaar lab @Penn, formerly @ChrisVakoc lab @CSHL. Also an avid eater and a dad.
Jeff Thompson @fvalstounge
162 Followers 65 Following Independent researcher. Currently focused on novel technologies and immunology to fight cancer.
Kat Mueller, PhD @kpmueller1
754 Followers 2K Following Postdoc @EvanWeberPhD @ChildrensPhila | Fellow @CancerResearch | Fellow @IDEAL_Research | #CART | #SingleCell |#InclusiveTeaching | She/Her 🏳️🌈
Kyle G Daniels @ScienceKyle
3K Followers 1K Following Assistant Professor @Stanford University Genetics. Synthetic Biologist // Real Human 🧬 🔬 💻 🏳️🌈 🏊🏾♂️
immunoboys, MD/PhD @immunoboys
2K Followers 1K Following An unholy amalgation of T cell tamer @dlwagner13 and kidney lover @lost_endorf
Dimitrios L. Wagner @dlwagner13
1K Followers 1K Following Assistant Prof, MD/PhD @cagthouston @bcmhouston & @ChariteBerlin // Genome Editing and Immunology // Views are my own // 50% of @immunoboys // dlwagner @Bluesky
Caitlin Zebley, MD Ph... @CaitlinZebley
300 Followers 164 Following Pediatric Bone Marrow Transplant, Immunology @stjuderesearch via @umnpedsres
kathy merrell @khmerrell
53 Followers 640 Following
Mohankumar @Mohanku78436347
22 Followers 639 Following
Waggoner Lab @LabWaggoner
13K Followers 8K Following Research lab of Dr. Stephen Waggoner. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer. @labwaggoner.bsky.social
Derya Unutmaz, MD @DeryaTR_
337K Followers 8K Following Professor scientist, immunologist, biomedical engineer & Biohacker. ALL IN ON AI ! #Longevity #BioAI #Codex #Robotics #Space #Scifi #Singularity #trekkie 🖖
Allison Betof, MD, Ph... @DrBetofMDPhD
5K Followers 2K Following Director of Advanced Melanoma Program, Director of Solid Tumor Cell Therapy @StanfordCancer | dog mom🐾/CF-L2 | FCOI: https://t.co/BQzZa9DdO7…
Accession Therapeutic... @AccessionTX
9 Followers 36 Following With its stealth virus platform technology, Trocept, Accession Therapeutics is focused on treating some of the most intractable and widespread forms of cancer.
Anusha Kalbasi @xrtcell
704 Followers 416 Following cancer immunology - sarcoma - melanoma - radiation oncology - https://t.co/ZhHn8j94Nm @stanford
Sneha Ramakrishna @SRamakrishna_MD
16 Followers 139 Following Assistant Professor @StanfordMed focused on #CART for pediatric solid and brain tumors
David Usharauli @3DiMMUNE
3K Followers 14 Following Immunologist & Biotech Co-Founder @Tregeutix on a mission to harness the power of Tregs & microbiota | Calling on visionary investors to join our journey 🚀
Ryan Nipp, MD, MPH, M... @RyanNipp
5K Followers 576 Following Oncologist and cancer outcomes researcher at the @UofOklahoma @OUCollegeofMed @StephensonCC || Passionate about improving cancer care || #PallOnc #GeriOnc
Chris Tape @christophertape
4K Followers 2K Following Group Leader at @uclcancer. Studying how different cell-types collaborate to drive cancer.
Uromigos @Uromigos
8K Followers 483 Following The Uromigos strives to provide balanced, scientific content related to care of patients with GU malignancies. Click the link below to listen to our podcasts.
Nature Reviews Cancer @NatureRevCancer
77K Followers 1K Following Nature Reviews Cancer is a monthly review journal for researchers working on cancer. We, the editors, highlight the most exciting topics in cancer research.
Kate Cwynarski @CwynKate
3K Followers 608 Following #Lymphoma @UCLH. Professor UCL. Chair UK T cell lymphoma working group. Past chair UK CNSL study group. views my own. #WiL #lymsm
Yakup Ergün @dr_yakupergun
7K Followers 324 Following Medical Oncologist / Bower Hospital / Evidence-based insights on cancer care / #bcsm #crcsm #lcsm #cancer
John P. Murad @JohnPMuradPhD
23 Followers 48 Following Cancer researcher, husband, and father. Secretly aspiring rockstar.
NIH Funding @NIHFunding
55K Followers 30 Following Official account on NIH grants and funding information: funding opportunities, policy news, & more. https://t.co/mt3gbuKOjg Engagement ≠ endorsement
Nick Haining @nickhaining
3K Followers 1K Following CSO and co-founder of @ArsenalBio via @DanaFarber, @broadinstitute, and @Merck. He/his.
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128K Followers 124 Following Be better than before. Cancer Bio, Immunology, Bio-Computation, 🏳️🌈, UAP/SETI. Negative posters blocked w/o pause.
Jeremy Grenier MD PhD @JGrenierMDPhD
149 Followers 182 Following Pediatric Hematology-Oncology Fellow
Documenting Saylor @saylordocs
107K Followers 1 Following Follow for Daily Bitcoin data, updates and Saylor insights
Society for Immunothe... @sitcancer
20K Followers 6K Following Society for Immunotherapy of Cancer (SITC) - Dedicated to improving cancer patient outcomes by advancing the field of tumor immunology and cancer immunotherapy.
Abdel-Wahab Lab @AbdelWahablab
5K Followers 1K Following The Abdel-Wahab Lab studies the functional genomics of hematologic malignancies, focusing on mutations in members of the spliceosomal complex.
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Yang Zhao @YangZhao102
163 Followers 198 Following T cell engineering & cytokine signaling in the Garcia lab｜Postdoc @Stanford_MCP ｜CRI fellow @CancerResearch | PhD @EPFL
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Molecular Therapy Fam... @MolTherapy
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Coinbase 🛡️ @coinbase
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Coinbase Assets 🛡�... @CoinbaseAssets
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33K Followers 3K Following Founder @citizenriflemen | Part Time Farmer | Bonsai Tender | Combat Vet | Frmr Swan Private | Frmr Gold Fund
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304 Followers 143 Following Postdoctoral researcher 👩🏻🔬 | Porteus lab | @Stanford Previously: PhD student | Beavis lab | @PeterMacCC I ❤️ CRISPR, synthetic biology & cell therapies
Andrew James Innes �... @andrewinnes007
411 Followers 795 Following Doctor & Scientist. Likes:James Bond, Leukaemia (it’s a love/hate thing), MPN, bone marrow transplant and cancer genomics 🧬. Own views. He/him.
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388 Followers 272 Following Wife, mom and coffee addict working to cure pediatric cancer. Assistant Professor of Pediatric Hematology/Oncology at UVA.
Simone Minnie @simone_minnie
1K Followers 414 Following Assistant Professor @UCSF | Minnie Lab | #Myeloma Research | #Immunotherapy | #ASCT | #CAR-T | Opinions are my own 👩🏻🔬🇦🇺 https://t.co/fUtrCPLQDL
Wansang Cho @ScienceWansang
34 Followers 126 Following Postdoc @Stanford Immune cell engineering in @ScienceKyle Lab. BS/PhD @SeoulNatlUni Chemical biology/drug discovery. Build better immunotherapy.
Biotech Shoutouts @BiotechSho99376
1K Followers 229 Following Here to call out dumb things in biotech - of which there are so very many. Views are my own, from public sources, and not investment advice.
derek guy @dieworkwear
1.5M Followers 1K Following Menswear writer. Editor at @putthison. Bylines at The New York Times, The Financial Times, Politico, Esquire, and Mr. Porter
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174 Followers 252 Following Assistant Professor @fredhutch working on building better T cell immunotherapies for cancer
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