ADAPT-Sepsis @AdaptSepsis
Biomarker-guided duration of antibiotic treatment for sepsis warwick.ac.uk/fac/sci/med/re… NIHR HTA commissioned trial Joined November 2018-
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A simple blood test can tell doctors when it is safe to stop antibiotics in patients recovering from #sepsis, a review has found. The work supported by @NCAlliance_NHS & other GM organisations & co-authored by @DarkNatter is published in @Anaes_Journal manchester.ac.uk/about/news/tes…
Cost effectiveness of PCT-guided antibiotic discontinuation explored link.springer.com/article/10.118…
Primary outcome @UKCCRGroup @AdaptSepsis . Safe reduction in antibiotics @DarkNatter #UKCCRF25
@DarkNatter presents @AdaptSepsis #UKCCRF25 lovely presentation
Delighted to have the chance to address important international discussions about @AdaptSepsis jamanetwork.com/journals/jama/…
Editor’s choice from the February 25 issue. ➡️ Camrelizumab With Chemotherapy in Patients With Early or Locally Advanced TNBC ➡️ Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis ➡️ Essential Thrombocythemia: A Review; and more. ja.ma/4hR14SI #JAMA #MedicalResearch #ClinicalTrials
@WICSBottomLine @hqva Thank you for this detailed review and comments. We @AdaptSepsis are working on trial process evaluation and health economic outcomes right now, so more to come to aid understanding of results. Hopefully, we will see you all @ICS_updates events in 2025 for further discussions
@CarrolEnitan @LancetChildAdol Congratulations on delivering and reporting an important study 👏 👏 👏. Looking forward to more discussions together and with @Pronto_Trial soon. @NIHRresearch @DarkNatter @DarkNatter@bsky.social
1/ Delighted to report the results of the Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH) trial in @LancetChildAdol thelancet.com/journals/lanch…
A major UK patient trial of a new biomarker testing protocol for sepsis, led by @OfficialUoM researchers, has shown it is possible to safely stop antibiotic treatment earlier than current care 🔬 @FBMH_UoM @DarkNatter Read more about the trial 👇 manchester.ac.uk/about/news/bio…
@darknatter presents the results of the @AdaptSepsis trial results earlier today at @CCRdownunder The paper has been published in @JAMA_current jamanetwork.com/journals/jama/…
Chief Investigator @darknatter shares the findings from the #ADAPTsepsistrial at #CCRdownunder @adaptsepsis @FBMH_UoM @NIHRresearch @EPPiC_Warwick @NCAresearchNHS @JAMA_current
We are delighted to have contributed to this important trial. Because clinical research is how we improve the care we deliver. Thank you to our patients who took part. @AdaptSepsis @NCAresearchNHS @DarkNatter
Published in JAMA with #CCRdownunder: In critically ill adults with suspected sepsis, antibiotic regimens were safely reduced when guided by measurement of procalcitonin but not by C-reactive protein. @CritCareReviews ja.ma/41t10TE
Fantastic work led by @darknatter and delivered by the phenomenal UK Critical Care community. We can safely reduce antibiotic duration using procalcitonin (but not CRP). @AdaptSepsis @WarwickCTU
Published in JAMA with #CCRdownunder: In critically ill adults with suspected sepsis, antibiotic regimens were safely reduced when guided by measurement of procalcitonin but not by C-reactive protein. @CritCareReviews ja.ma/41t10TE
We're delighted to announce @AdaptSepsis as our first trial result presentation at #CCRdownunder ADAPT-Sepsis is a 2760 patient RCT investigating biomarker-guided duration of antibiotic therapy in patients with sepsis To be presented by @DarkNatter criticalcarereviews.com/meetings/ccr-d…
From Belfast to Melbourne - CCR Down Under is coming The Best Critical Care Trials in the World #CCRdownunder criticalcarereviews.com/meetings/ccr-d… @intensiveblog @precordialthump @KBibbinsDomingo @giovannilandoni @GiacomoMonti @BaiardoMartina @anzicsctg @chodgsonANZICRC @DogICUma
Thrilled to hear that the @AdaptSepsis team have reached their recruitment target - well done everyone! We're looking forward to comparing our process evaluation findings with your trial results in the coming months! cedar.nhs.wales/our-work/clini…
Thank you to patient participants, families and carers for their generosity in taking part in the @AdaptSepsis research trial. We will now work hard with sites and investigators to complete data collection and report results as soon as possible @NCAresearchNHS @WCTU @FBMH_UoM
@DarkNatter @AdaptSepsis @NCAresearchNHS @WCTU @FBMH_UoM Congratulations, Paul, looking forward to the results!
Great work to all involved in completing recruitment to the @AdaptSepsis study. Thank you to our research team for their hard work in recruiting 85 of the number below! @NCAresearchNHS @OldhamCO_NHS
Thank you to patient participants, families and carers for their generosity in taking part in the @AdaptSepsis research trial. We will now work hard with sites and investigators to complete data collection and report results as soon as possible @NCAresearchNHS @WCTU @FBMH_UoM
@DarkNatter @AdaptSepsis @NCAresearchNHS @WCTU @FBMH_UoM Amazing!! Well done xx
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