BrittonLab @BrittonLab
Group run twitter account for the Britton Organic Chemistry Lab brittonsfu.com Simon Fraser University Joined November 2021-
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A nice summary of our recent work on the synthesis of nucleoside analogues has been published in Synfacts... check it out! #chemtwitter #nucleosides #oligonucleotides #organocatalysis #asymmetricenantioselectivesynthesis
We had a great time at Jackalope's Neighborhood Dive 🤘🏼🎸(Dr. Memo's favourite spot) celebrating our recent @J_A_C_S paper on the use of RAvIN Ketone building blocks for non-carbohydrate oligonucleotide synthesis! Make sure to check it out ! pubs.acs.org/doi/abs/10.102…
Check out what our lab and the @reiser_group stitched together contemporaneously. Both labs report a new olefination method via denitrative cross-coupling of readily accessible nitroalkanes on @ChemRxiv Parasram (image): chemrxiv.org/doi/full/10.26…. Reiser: chemrxiv.org/doi/full/10.26…
We are thrilled to introduce "The RAvIN Platform" published in @J_A_C_S !!!🚨 This work features the efficient preparation of nucleosides in high enantiopurity (99.9% ee) and the first non-carbohydrate total synthesis of an oligonucleotide therapeutic. pubs.acs.org/doi/10.1021/ja…
Last week's Paper-of-the-Week (POW) presentations in our weekly group meeting featured some great work by Morken Group, @BrittonLab + Pantophlet + @DrLCsquare, @CarreiraGroup, and Reisman Group + Peters Group! #chemistry #boron
New paper alert!!! 🚨🚨🚨 We report "A unified platform for nucleoside analog synthesis" in @ScienceMagazine Congratulations to Matthew, Ethan, the rest of the team and our @Merck collaborators @DrLCsquare and @asymtmm for this monumental publication! science.org/doi/10.1126/sc…
The group had a fun outing at CRAFT Brewery last week for our annual Britton Lab Christmas Party! The night was complete with tasty food, good brews, and our traditional "Pirate Santa" gift exchange. You can see from the video which of the gifts was a favourite 😆 #chemtwitter
Congratulations to Alan ( @AlanBrookeChem ) for his recent publication "A convenient synthesis of enantioenriched α-haloaldehydes" - now online in RCS - Organic Chemistry Frontiers ... Check it out !!! #chemtwitter #alphahaloaldehydes #methodology pubs.rsc.org/en/content/art…
A handful of group members had the chance to represent the lab with some excellent poster and oral presentations in beautiful Banff, Alberta this past week! Thank you to the @BanffSOC committee for organizing such a fun and interactive conference! #chemtwitter
Congratulations to Ethan for his published review on "Non-carbohydrate syntheses of nucleoside analogues", featuring our group's research on the synthesis of ribo-, imino-, thio-, and carbocyclic nucleoside analogues from simple achiral precursors! cell.com/trends/chemist…
Welcome to our newest PhD student Peter! We had a fun group outing last week to celebrate, enjoying some brews and pizza at Rewind Brewery :) #chemtwitter #teambonding
New publication out in @angew_chem on the "Synthesis and Diversification of Bridged Nucleoside Analogues" in collaboration with @Merck, @DrLCsquare, and @asymtmm ... check it out! #chemtwitter #nucleosides onlinelibrary.wiley.com/doi/10.1002/an…
Thank you to the @Stephenson_Lab for hosting us @UBC for our first joint group meeting! We enjoyed learning about the photoredox/electrochemical research your team undertakes and were excited to share a glimpse into our nucleoside/total synthesis research with you! #chemtwitter
Check out our latest publication in collaboration with @BCCancer featured in JACS!!! Big congratulations to Dr. Daniel Driedger as this was a substantial portion of his PhD thesis! This synthesis of Eleutherobin has been a long time coming (> a decade)!!! pubs.acs.org/doi/10.1021/ja…
We enjoyed an amazing BBQ outing yesterday at Strathcona Lookout Park in Deep Cove! The day was filled with fun on the water in paddle boards and canoes (thanks Rob!) along side some competitive spike ball games in the park :) #chemtwitter #teambonding
Congratulations to Daniel and Darryl for an excellent publication in @ChemicalScience !!! Showcasing an exhaustive and impressive chemical library of 170 polypeptide-like macrolides ... well done! #chemtwitter pubs.rsc.org/en/content/art…
Congratulations to Dr. @GarrettMuir (and other Britton lab co-authors) for this interesting investigation of Grignard reactions to C4'-modified nucleoside analogues in collaboration with @Merck , @DrLCsquare , and @asymtmm ... Excellent work everyone! nature.com/articles/s4146…
Britton Lab Christmas Dinner 2024 complete with delicious food from @CRAFTbeermarket and a fun Pirate Santa game🎁🎅🏼 with plenty of 'gift-stealing' (mainly the special cereal and lotto tickets). Merry Christmas and Happy Holidays from our lab to you and yours! #chemtwittter
Fresh article out now in @ChemicalScience !!! Well done to the team for the hard work put towards this exciting project! Yet another example of how ɑFAR aldol products are excellent and diversifiable precursors towards nucleoside analogues. #chemtwitter pubs.rsc.org/en/content/art…
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