Siling Du @DuSiling
Neuroimmu-enthusiast🧐GR6 IMM student in the Kipnis lab & Colonna lab at WashU| Studying brain macrophages & neurodegeneration | Re-tweet to learn St Louis, MO Joined December 2018-
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Very thrilled and grateful to see our work featured on the cover of @NeuroCellPress! Many thanks to our co-authors and collaborators who contributed to this study.
cell.com/issue/S0896-62… On the cover: In this issue of Neuron, Du et al. @DuSiling show that repeated microglial depletion enables peripheral monocytes from both the blood and skull bone marrow to infiltrate the brain and engraft as monocyte-derived macrophages with distinct
@NeuroCellPress Special thanks to Ying Xu for turning our rough concept into such a beautiful artwork!
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Decoding the spatiotemporal development of human meninges @CellCellPress cell.com/cell/fulltext/…
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nature.com/articles/s4158… -> organ specific ECM shapes identities of intrinsic nervous systems. v cool!
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Excited to share our new study out in @SciImmunology We show that Monocyte-derived Macrophages drive oxidative damage during neuroinflammation science.org/doi/10.1126/sc…
Congrats Haikuo! Beautiful work!
Check out our recent work on @NatureComms! Greatly appreciate my mentors and collaborators making this possible. We developed epi-Patho-DBiT, a unified platform that enables spatially resolved ATAC -seq or CUT&Tag analyses in FFPE tissues!
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Excited to announce our study (w/ @RukmanThota & @MaxKrummel) published today @Nature: Macrophages “hold our living identities” by taking tiny bites from living cells and presenting this information to CD8 T cells. nature.com/articles/s4158… #immunology #cellbiology @immunox @UCSF
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Somatic cancer variants enriched in Alzheimer’s disease microglia-like cells drive inflammatory and proliferative states: Cell cell.com/cell/fulltext/…
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I am very happy to share that our paper is now published in @Nature 😊 Cell-type-targeted mitochondrial transplantation rescues cell degeneration. nature.com/articles/s4158… @IOB_ch (1/6)
Siling Du retweeted
Just updated my HHMI Gilliam Fellowship application guide for the 2026 competition, which brings major program changes. Int'l PhD students can now apply. MD-PhDs are eligible. & a new postdoc pathway that can extend HHMI support up to 7 years total. yaelcourtney.com/resources-and-…
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Giving a talk soon on open box science + microglia taking the road less traveled. We started with a question about how tissue-resident macrophages develop and ended up uncovering a distinct regulatory program: Maf and Jun drive Zeb2 during primitive hematopoiesis.
OBS Immunology Immune cell ontogeny, and functional specialization of immune cells 🔹Laura Jiménez Gracia, PhD @cnag_eu 🔹Jing Chen @JingNeticist @washumedicine Moderator: @asalboix 📅 Tuesday, April 14 ⏰ 12 pm ET, 6 pm CET 💻 us02web.zoom.us/meeting/regist…
Siling Du retweeted
The Orange Cat Brain Atlas is here. 🧠🐈 Today, we published the first comprehensive cellular map of the orange cat brain. The new atlas reveals a single, specialized neuron responsible for behaviors like staring at walls, knocking objects off tables, and the 3am "zoomies."
Siling Du retweeted
Our live tissue clearing paper is out in @naturemethods! We achieved optical clearing of mammalian brain tissues without compromising normal neuronal function. Big congrats to @Shigenori774 and our wonderful collaborators! 🎉 nature.com/articles/s4159… (1/10)
@LuLiu_Laura Thank you Lu! And hope our newest version brings more fun to you :D
🧵Excited to share my thesis work out today in @NeuroCellPress from @kipnislab and @TheColonnaLab: "Brain-Engrafted Monocyte-derived Macrophages from Blood and Skull-Bone Marrow Exhibit Distinct Properties." 🧠🦴 sciencedirect.com/science/articl…
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