Ed Huttlin @EdHuttlin
I’m a scientist and spend most of my time thinking about proteomics, mass spectrometry, and bioinformatics - especially protein interactions. Boston, MA Joined May 2017-
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If you’re at #ASMS2026, stop by poster 649 today to hear about the latest developments in the BioPlex project! This time I’m focusing on what BioPlex can teach us about the ubiquitin-proteasome system.
#ASMS2026 is now under way! If you’re here, don’t miss these talks and posters from @GygiLab members this week. See you there! Thanks to @AmandaLSmythers for the nice graphic!
Check out new work published in @ScienceMagazine from a wonderful collaboration led by the lab of @JiefuBiol @hhmi_science to map the luminal surface of brain vasculature proteome to uncover BBB regulators @BroadProteomics @broadinstitute
Luminal surface proteome of the brain vasculature uncovers blood-brain barrier regulators @ScienceMagazine: science.org/doi/10.1126/sc… Big thanks to Zijian, Zuzhi, Yupu, Khanh, Yuxiang, and all collaborators to make this possible!
To better understand the ubiquitin-proteasome system, Suzanne Elsasser, Dan Finley, and the Human Proteostasis Consortium have systematically surveyed its components: biorxiv.org/content/10.648… I would encourage you to check out this valuable resource! @harvardmed
This morning’s course on studying protein-protein interactions is well on its way at #USHUPO2026! I just wrapped up my talk on AP-MS, and now Lan Huang is talking about crosslinking MS. This afternoon Ling Hao will be talking about proximity labeling as well. @us_hupo
The #NobelPeacePrize medal. It measures 6.6 cm in diameter, weighs 196 grams and is struck in gold. On its face, a portrait of Alfred Nobel and on its reverse, three naked men holding around each other’s shoulders as a sign of brotherhood. A design unchanged for 120 years. Did you know that some Nobel Peace Prize medals have been passed on after the award was given? A well‑known case is Dmitry Muratov’s medal, which was auctioned for over USD 100 million to support refugees from the war in Ukraine. And the medal displayed at the Nobel Peace Center is actually on loan and originally belonged to Christian Lous Lange, Norway’s first Peace Prize laureate. But one truth remains. As the Norwegian Nobel Committee states: “Once a Nobel Prize is announced, it cannot be revoked, shared, or transferred to others. The decision is final and stands for all time.” A medal can change owners, but the title of a Nobel Peace Prize laureate cannot.
Video message from Federal Reserve Chair Jerome H. Powell: federalreserve.gov/newsevents/spe…
@RebeccaFHough @KJP We watched this every year when I was growing up, and my siblings, parents, and I still frequently reference it around Christmas.
Unexpected Kid Math Question: how many digits of pi do you need to look at to find the series “67”? Answer: 100 If you’ve been wondering, you’re welcome!
Dear American friends, Europe is your closest ally, not your problem. And we have common enemies. At least that’s how it has been in the last 80 years. We need to stick to this, this is the only reasonable strategy of our common security. Unless something has changed.
If you’re at #HUPO2025, be sure to stop by my poster and learn about the latest developments in the @HMSBioPlex project!
Harvard researcher Joan Brugge says her work has the potential to prevent breast cancer, but she was notified last spring that her federal funding was terminated. “It was just like a gut punch. My knees buckled, and I had to sit down,” she says.
Kudos to the organizers (@JGMProteomics, @mlaval6, Marie Brunet) for arranging snow to coincide with the start of HUPO 2025 in Toronto!
I’m at the airport a and ready to fly to Toronto for this year’s HUPO conference. I’m looking forward to talking about AP-MS tips and tricks at tomorrow’s pre-conference workshop on protein-protein interactions and sharing our latest @HMSBioPlex results in a poster on Wednesday!
Check out this thread to learn about some cool new work from @echouchani, @HaopengXiao, and their teams read of the authors! I was happy to help out on a small part of what has turned out to be a cool story.
Excited to share a new paper and online resource from our lab published today. We developed a mass spectrometry approach that leverages genetic diversity to systematically nominate functional relationships between metabolites and proteins. nature.com/articles/s4158…
thecrimson.com/article/2025/9… Harvard Funding Cuts Endanger the Massive Fruit Fly Database That Powers Genetic Research
We are looking for a talented Postdoc to join our Lab @MDAndersonnews ! If you're interested in metabolism, tumor microenvironment, and cutting-edge MS proteomics, and have less than 2 years Postdoc experience, look here 👇 jobs.mdanderson.org/search/jobdeta…
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