Yihao Yang @EpiYang
📍Altos Labs, San Diego | 🧬 Studying the aging epigenome Joined April 2019-
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New Science Blog: Why has AI advanced faster in coding than in biology? To agents, bio databases are like cities built before cars—maddening to drive in because they're designed for different traffic. How do we build infrastructure agents can use? anthropic.com/research/agent…
Exciting breakthrough technology from the lab, now live in @CellCellPress ! Instead of cutting the genome where proteins bind (e.g., Cut&Tag), D&D-seq scars the DNA with a deaminase, allowing single cell genome mapping of TFs and chromatin remodellers!
Oh my god, almost no biomedical AI papers had proper validations. This feels like field-wide malpractice.
In a meta-analysis of 210 biomedical AI studies that statistically compared models under cross-validation, 97% used invalid statistical tests. Here's our new preprint doi.org/10.64898/2026.… led by @tianchuzeng @kkli20111 @ZShaoshi @ten_photos 1/N
Personal update: I've joined Anthropic. I think the next few years at the frontier of LLMs will be especially formative. I am very excited to join the team here and get back to R&D. I remain deeply passionate about education and plan to resume my work on it in time.
"They're having problems with their economy again." Ron Cobb 1975
@YourAnonCentral I sincerely hope that if he dies of a stroke, someone runs this photo next to his obit.
I bookmarked this for a reason….
Reporter: On the ballroom, in July the WH said it was going to cost $200 million. Yesterday the president said $300 million. Why did it go up by so much? Leavitt: It’s not going to cost the taxpayers a dime.
Three nationalities left out of the list. Possibly coz their high contribution along with the color of their skin doesn’t align with the narrative. Indian : $1.7 million Chinese : $800K Filipino : $600K
We built an AI that will tell you what will get your grant rejected. It’s a tough critique, but it’s better to know when you can still do something about it 👇 @qedScience
REPORTER: You mentioned that, staying on as Fed governor, you intend to keep a low profile. Could you give us a little more detail on what that looks like? JEROME POWELL: *ducks down*
Unfortunately this is true….. @MicrobiomDigest
This paper got a few million views across various RTs two weeks ago: EMF remote-controlled mice... Look carefully at the saline & control images from the paper -- can you see how the two images are flipped and re-cropped? h/t @AndrewGYork and friends for the close read
fuck you
Why is it that a Democrat is never shot at?
Shooting oneself in the foot? Nope. Shooting oneself in the prefrontal cortex.
U.S. President Donald Trump has fired all 24 members of the National Science Board, the body that oversees the National Science Foundation. Many science advocates see it as the latest step by his administration to erode—some would say destroy—the independence of the 76-year-old
BREAKING: A Syrian billionaire needed U.S. sanctions lifted so he could cash in on $12 billion in reconstruction contracts, per NYT. In an attempt to influence American foreign policy, he proposed a Trump-branded golf course, cut Jared Kushner & Ivanka Trump into a multibillion-dollar real estate deal for a resort in Albania, and had someone physically deliver a stone engraved with the Trump family crest to a Republican Member of Congress with instructions to take it to the White House to get the President's attention. Trump threw his weight behind repealing the sanctions. They were lifted. The contracts are moving, and the Trump family’s deals are expanding.
Benchmarking single-cell foundation models for real-world RNA-seq data integration biorxiv.org/content/10.648…
Frontier models aren't ready for end to end genomics analyses yet. But I wonder how an average grad student would do on these problems...
Excited to share GeneBench, a genomics eval I've developed w/ @OpenAI that measures whether current models can execute realistic end-to-end scientific analyses where good scientific judgement is required. tl;dr they’re getting close, but aren’t quite there yet
90% of AI biotech startups are just: > take disease target from PubMed > link Google Scholar API to Claude > generate a summary on the least cited target > raise $40M Series A on "AI-powered drug discovery"
90% of "AI startups" are just: Take user input Send to OpenAI API Display response Charge $29/month
Another Jan. 6 rioter pardoned by President Donald Trump will plead guilty in a separate case involving child exploitation of multiple victims, according to federal court records. on.nbc7.com/vBQnu2M
Inflation was coming down in the United States—and then Trump’s tariffs happened.
WE. REACHED. A. FUCKING. AGREEMENT. WITH. THEM. IN. 2015. THAT. IMPOSED. STRICT. LIMITS. ON. URANIUM. ENRICHMENT. UNTIL. 2040. It was called the JCPOA. And Trump TORE IT UP IN 2018 out of spite for @BarackObama 8 years later, here we are. Total. Disaster.
Cam Bambi 🦌 @Katemagee1
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Nancy V @lhira07
19 Followers 734 Following living in my head, visiting reality sometimes 🧚 follow back
Manel Esteller @ManelEsteller
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avi®︎ @Kzk831
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Epigenome Technologie... @EpigenomeTech
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Gilderoy Wockhardt @Wockcrafter
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ELON @ELONzf8
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Luis F. Soto-Ugaldi @LFSoto12
201 Followers 428 Following Bach. Genetics and Biotechnology Ph.D. student in Computational Biology at Fuchs Lab and Pe'er Lab RU/MSKCC
Center for Epigenomic... @CEpigenomics
2K Followers 536 Following Est. @UC San Diego to answer human health and science questions through epigenomic research, tech & partnerships. https://t.co/MC9Q0wHNiA (Director: Bing Ren)
Black Jesus @blackjes_black
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Jinlong Y. Lu @JYuyangLu1
44 Followers 117 Following Senior Scientist II @ Altos Labs; Former Postdoc @ Gorbunova & Seluanov lab; Former Ph.D. @ Xiaohua Shen Lab; Views my own.
Joanna Yeung @JoannaYeung7
197 Followers 327 Following Yeung at heart ✨✨✨ | Risca Lab | https://t.co/uMsKLatLW0 Co-founder of @shesthinkingco | Ph.D Candidate at Rockefeller, dying 🙃(@IsShihARoach, @yaeltea)
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209 Followers 200 Following Graduate Fellow @Victora_Lab @RockefellerUniv | BIF PhD Fellow | Previously Visiting student in #TavazoieLab | @uniheidelberg Biochemistry alum
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Claude @claudeai
1.5M Followers 2 Following Claude is an AI assistant built by @anthropicai to be safe, accurate, and secure. Talk to Claude on https://t.co/ZhTwG8d1e5 or download the app.
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1.3M Followers 2 Following We're an AI safety and research company that builds reliable, interpretable, and steerable AI systems. Talk to our AI assistant @claudeai on https://t.co/FhDI3KQh0n.
Gladstone Institutes @GladstoneInst
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1K Followers 1K Following Dev Bio Program + Center for Stem Cell Biology @MSKCancerCenter. Building next-gen cellular models to study brain development and disease.
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Political Polls @PpollingNumbers
373K Followers 436 Following Our non-partisan group informs you with political polls, predictions, and election night results. To Advertise Pls PM us.
NYTimes Communication... @NYTimesPR
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2.8M Followers 1K Following "You cannot escape the responsibility of tomorrow by evading it today.” – Abraham Lincoln 🏴☠️ | Home of #TheBreakdown and LP Podcast
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Tim Walz @Tim_Walz
1.1M Followers 2K Following Dad, husband, teacher, coach, veteran. 41st Governor of Minnesota. Official account: @GovTimWalzYou might like
