GoggleDocs @GoggleDocs

🥽🩺Docs/nurses/pharmacists from U.K. Talking CardioRenoMetabolic & more Catch us on YouTube https://t.co/VSFSwEDXDD |Educate, Motivate, Activate! London, England Joined October 2020

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Daniel J Drucker @DanielJDrucker

2 days ago

The next chapter from Prof Steven Kahn clearly conceived before #ADA2026 now more timely, published in @DiabetesCareADA diabetesjournals.org/care/article/d… #Diabetes

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GoggleDocs @GoggleDocs

4 days ago

An Open Letter to the American Diabetes Association: Shame on You c.org/brTFTjVw via @Change

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#ADA2026 #Zenagamtide (Amycretin) Delivers in #T2D 💥 Dual GLP-1 + amylin agonist shows impressive HbA1c & weight reductions with no apparent weight-loss plateau 🧪 Phase 2b (n=226; T2D on metformin ± SGLT2i) 🩸 HbA1c: ⤵️1.41%(10mg) − 1 .71% (40 mg) vs ⤵️0.14% (pbo) 🎯 HbA1c ≤6.5% achieved: 76% (40 mg) vs 14% (pbo) 📉 Mean weight loss at 36 wks: ⤵️12.9(10mg) − 14.6% (40 mg) vs ⤵️2.1% (pbo) 📊 CGM metrics improved across all doses 🤢 GI AEs were the most common, with rates broadly consistent with GLP-1 and amylin therapies 💡 Notably, the 20 mg group had only 8w at maintenance dose and the 40 mg group only 4w, yet weight loss curves were still trending downward at 36w 👉 One of the strongest combinations of glycaemic and weight efficacy seen to date in T2D❗️ 📌 Poster 1730-P

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Dr. Alice Cheng @AliceYYCheng

6 days ago

This is shocking 😮. Just happened at the start of #ADA2026 Scientific Sessions.

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GoggleDocs @GoggleDocs

7 days ago

🚨 DiRECT 5-yr data in Diabetic Medicine 👉Primary care low-energy diet: 6.1 kg weight loss, 10% T2D remission at 5 yr (46% → 36% → 10%). 💰Modelled cost dominance over usual care. Lifetime QALY +0.08, cost -£496. 10% reads as failure to some. It isn't. Obesity and T2D are chronic relapsing conditions. Remission ≠ cure. The clinical point worth flagging: 🔹 Patients pursue remission to come off meds. Fair 🔸 Remission isn't licence to drop evidence-based CV prevention 🔹 NICE increasingly puts metformin + SGLT2i as starting point for many adults with T2D 🔸 Statins still matter. CTT: ~22% major vascular event reduction per 1 mmol/L LDL fall 🔹 BP and lipid control need reassessing after remission, not assuming resolved Incretins offer larger weight loss and hard CV data in selected groups (SUSTAIN-6,SELECT, FLOW). DiRECT doesn't. It's a tool. Use it wisely. 🔗 doi.org/10.1111/dme.70…

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GoggleDocs @GoggleDocs

a week ago

@cpgale3 What’s going on in East London?

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GoggleDocs @GoggleDocs

a week ago

🔍 10% Visceral Fat loss⤵️ T2D cases by 28% over 10y 5- and 10-yr follow-up of two 18-mo lifestyle RCTs. The story isn’t the weight loss. It’s what stayed lost after the weight came back: 🔹 VAT -27% at 18 mo (MRI) 🔸 5–10 yr later: weight fully regained. VAT still ~15% below baseline (~55–60% of original loss preserved) 🔹 Each 10% VAT loss = 28% lower T2D risk in follow-up (HR 0.72). Association, not proof 🔸 Liver and pancreatic fat fully regained Track waist, not just weight. 🔗 doi.org/10.1161/CIRCUL…

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GoggleDocs @GoggleDocs

2 weeks ago

@parthaskar 💔 “Grief is the price we pay for love.” - Colin Murray Parkes. Thinking of you and your family.

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GoggleDocs @GoggleDocs

3 weeks ago

@parthaskar @RCPhysicians @DrLKVaughan @DrAsifQasim @COPDdoc @respirologist @DrSelvarajah @DrSteveTaylor @doctor_katie @ShivaniM_KC @HamidIftikhar33 😳

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Partha S Kar 🇮🇳🇬🇧🏏🎥 @parthaskar

3 weeks ago

The attempts of the @RCPhysicians to cling on to the vestiges of what they once supported is quite ...amazing The requirements to be... Certificate in Geriatric Medicine Knowledge-Based Assessment Lead includes being a PA for 7 years. I predict this is a degree anyone can do and be equated to specialist training in near future too. @GeriSoc - are you saying a Consultant of 3 years experience and a PA of 7 years experience are at par? Cos that's....something Link: bgs.org.uk/vacancy-certif…

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GoggleDocs @GoggleDocs

3 weeks ago

🚨 TRIUMPH-1: #retatrutide topline data🚨 Phase 3, n=2,339, 80 wk, obesity without diabetes (efficacy estimand): 🔹 12 mg: -28.3% body weight (-31.9 kg) 🔸 9 mg: -25.9% | 4 mg: -19.0% | Placebo: -2.2% 🔹 ≥30% weight loss: 45.3% vs 0.5% 🔸 104-wk extension (BMI ≥35, n=532), 12 mg → MTD: -30.3% Cross-trial context (obesity, no diabetes): 🔹 STEP-1 SEMA 2.4 mg, 68 wk: -14.9% 🔸 SURMOUNT-1 TZP 15 mg, 72 wk: -20.9% 🔹 TRIUMPH-1 RETA 12 mg, 80 wk: -28.3% ⚠️But: 🔸 Topline press release. No peer-reviewed publication yet 🔹 AE discontinuation at 12 mg: 11.3% vs 4.9% placebo 🔸 Dysesthesia 5.1–12.5% vs 0.9%. Efficacy ceiling keeps moving. Enthusiasm needs caution. Still unlicensed in humans outside of research❗️ 🔗 investor.lilly.com/news-releases/…

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GoggleDocs @GoggleDocs

3 weeks ago

To be honest there are a lot of unknowns about this. In terms of diabetic retinopathy the postulated theory remain rapid drop in glucose exacerbation the retinopathy. Although they are GLP-1 receptors within the retina. In terms of normal glucose in an obese population without T2D less is known and particularly in non diabetic retinopathy. Other than what you have seen

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Partha S Kar 🇮🇳🇬🇧🏏🎥 @parthaskar

3 weeks ago

Age of diagnosis; #T1Diabetes #T2Diabetes & science “Clinicians should be aware that patients progressing to #insulin within 3 years of diagnosis have a high likelihood of #type1diabetes, regardless of initial diagnosis” Via @DiabetologiaJnl Please use, RT as possible Link: pubmed.ncbi.nlm.nih.gov/30969375/

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GoggleDocs @GoggleDocs

4 weeks ago

The opportunity this provides and potential is there… if science builds further and regulation/policy/funding allows… hopefully will go the way of tech all those years ago …. Would like to get to a point to say the next 5 years is about cementing and implementing immunotherapy in T1D… not there yet though…

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Partha S Kar 🇮🇳🇬🇧🏏🎥 @parthaskar

4 weeks ago

Some weekend reading for those interested in...science For ever more? Treatment of #T1Diabetes has relied on #Insulin And the 'cure' is forever '10 years away' Yet...what hope does science offer...what are the areas of intrigue and interest? A fabulous article via @jclinicalinvest - and the vision of immune tolerance. @ShivaniM_KC @DanielJDrucker @aaronjkowalski @BreakthroughT1D @BT1DUK @DiabetesUK Link: jci.org/articles/view/…

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Partha S Kar 🇮🇳🇬🇧🏏🎥 @parthaskar

4 weeks ago

Some early morning #Diabetes education on a Friday…. Why not. “Is that HbA1c correct?” Have a look at the wider picture 🙂 Use, RT as you wish #T1D #T2D

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Cristina Tejera @cristinatejerap

4 weeks ago

¿Cuándo elegir semaglutida y cuándo tirzepatida? La EASO acaba de actualizar su algoritmo con evidencia hasta noviembre 2025 📊 @EASOobesity Spoiler: depende del objetivo clínico. No es solo pérdida de peso. 🔗 @NatureMedicine nature.com/articles/s4159… #ECO2026

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Dr Amar Puttanna 🎸 @AmarPut

a month ago

Interesting data from #ECO2026 @EASOobesity Building on the need for more data in women’s health esp around menopause but more interesting is the migraine data Expanding the other potential beneficial effects of weight loss and why there are also trials in IIH with incretins

Novo Nordisk @novonordisk

a month ago

#PRESS Our new data presented at the European Congress on Obesity highlights the powerful, consistent weight loss that our obesity injection delivers for women across all menopause stages. The data reveals that it also lowers risk of migraine, depression and cardiovascular

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Kevin Fernando @drkevinfernando

a month ago

🔥My latest Medscape Primary Care #Hack is live! 💡Continuous Glucose Monitoring #CGM for people living with #T2D Co-authored with @drheatherbell Includes 8 simple steps to interpreting the Ambulatory Glucose Profile report #AGP PDF download link in comments 👇