Simon Grelet @GreletLab
Cancer Innervation and Neurobiology Lab at the Mitchell Cancer Institute University of South Alabama Cell-cell transfers of mitochondria - RNA biology Mitchell Cancer Institute Joined March 2024-
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Simon Grelet retweeted
#mitochondrialTransfer as a therapy for disease moves closer to reality with @IOB_Roska's new #MitoCatch approach targeting specific cell types! Read about the @Nature paper, with author Q&A on next steps to the clinic: #UMDF #mitochondria @mitoscientists mitoworld.org/cell-type-targ…
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Simon Grelet retweeted
The revolutionary #AACR26 session #mitochondrialTransfer Networks in #Cancer Progression shared revelations on central roles of #mitochondria from @GreletLab, L Gattinoni & Y Togashi. Read the groundbreaking insights! @AACR #CancerResearch #UMDF #mtDNA mitoworld.org/mitochondria-c…
Simon Grelet retweeted
Computationally designed “tree rings” for recording cellular history 🤯 I love synthetic biology inspired by mother nature’s tricks. Congrats to the authors
🚨 Today in @Nature, we report GEMINI—a genetically encoded intracellular memory device that writes cellular dynamics into tree-ring-like fluorescent patterns within cytoplasmic protein assemblies.[1/n] nature.com/articles/s4158…
Simon Grelet retweeted
🚨 Today in @Nature, we report GEMINI—a genetically encoded intracellular memory device that writes cellular dynamics into tree-ring-like fluorescent patterns within cytoplasmic protein assemblies.[1/n] nature.com/articles/s4158…
See you in Phoenix! I will be speaking at the @aaas Annual Meeting 2026, where I will present our work that was selected by @ScienceMagazine Breakthroughs of 2025. “Neurons Make a Deadly Donation to Cancer Cells,” Friday, February 13, 2026 11:30 AM-12:30 PM MST Phoenix, AZ
Simon Grelet retweeted
Cancer cells use mitochondria stolen from immune cells to spread and escape detection go.nature.com/3NjP9m1
Simon Grelet retweeted
Nature research paper: Mitochondrial transfer from glia to neurons protects against peripheral neuropathy go.nature.com/49JCz85
Simon Grelet retweeted
“Wherever anything lives, there is, open somewhere, a register in which time is being inscribed.” - Henri Bergson (Creative Evolution, 1911). Superb start to this paper: cell.com/cell/fulltext/… @CellCellPress "Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma"
@BrestoffLab @NatMetabolism Congratulations! This is well deserved for such an important review.
Simon Grelet retweeted
Neurons can support cancer initiation, growth and migration and can drive therapy resistance through various mechanisms go.nature.com/494eJmi
Simon Grelet retweeted
KJ Muldoon, at less than a year old, was the first known person to receive a personalised CRISPR-based genome-editing therapy He is part of Nature’s 10, a list of people who shaped science in 2025 go.nature.com/4sh778K
@EricTopol @ScienceMagazine Thank you @EricTopol for sharing!
Simon Grelet retweeted
How neurons transfer mitochondria to cancer cells to promote metastasis, a 2025 @ScienceMagazine Breakthrough runner up nature.com/articles/d4158… nature.com/articles/s4158…
Simon Grelet retweeted
Mitochondria move thru the body. Free mitochondria can be exported by brown fat cells into the bloodstream. From there, they transit to cells with damaged mtDNA, where they are imported and rescue mitochondrial function. The implications for cancer therapies are profound. nature.com/articles/s4158…
Simon Grelet retweeted
Holy Soma Batman! You never know what you may find when you cruise our MICrONS Explorer, such as a blood vessel piercing the soma of a neuron! 👀 See this incredible find up close using this shortcut: ngl.microns-explorer.org/#!%7B%22layers…
Simon Grelet retweeted
MOSAIC lattice light sheet xy projection over 2+ hrs in human retinal pigment epithelial cells of endoplasmic reticulum remodeling (cyan) and transport of vesicles (yellow) containing β4-galactosyltransferase....
Simon Grelet retweeted
MOSAIC large field of view 3D single molecule localization microscopy of mitochondrial outer membranes and nuclear membranes in fixed U2OS cells.
Simon Grelet retweeted
"I think the classic adage that the prepared mind is necessary to take advantage of the fortuitious circumstances that an individual has is absolutely right." Cell biologist Craig Thompson discusses the role of intuition in making scientific decisions in this #AskAScientist.
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