🔬Biomedical Engineering🧪at San José State University
PI: Dr. Patrick Jurney
Expertise: Biomaterials, Microfluidics, Endothelium, & Nanoparticle Drug DeliveryJurneyLab.org Silicon Valley, CAJoined September 2021
A different kind of publication: Our @sjsu magazine has written a very cool story about our lab and the @NIGMS-funded research that our team is doing down here in #siliconvalley.
Our team is incredible. and the future is bright!
Story here: sjsu.foleon.com/washington-squ…
@jurneylab MS student Ammar Babiker is presenting his work to standardize an endothelialization protocol for vascular biomaterials. #BMES2023 stop by today 2-3:30 at poster 404 in the main exhibit hall. @BMESociety
@NPeppas@UTAustin@UTBiomedical Prof. Diller's biological heat transfer course changed how I think about engineering and the impact that we can have. Happy to hear that he's been honored in this way, thank you if you're listening!
Wonderful day of talks and vibrant discussion between students of @BmeSjsu@SJSUEngineering @SJSU and leaders in the bay area biomedical device industry at @23bayareabiomed. Here are Saumya, Rhea,and Eyerusalem from @JurneyLab discussing their work. #proudPI#SJSUBioMed2023
Our lab will be sharing our work understanding the vascular adhesome to improve vascular biomaterials, which is funded by @NIHgrants through @NIGMS. join us if you're interested in the work or finding stories. @calstate@SJSUResearch@SJSUEngineering
Know any high school students curious about bioengineering? We will offer @Stanford's Intro. to Bioengineering for credit at no cost to students in Title 1-eligible schools. Info. session THIS Thursday: publicate.it/p/i23zEQAyQcXW… Grateful for retweets. @EdEquityLab @jennbrophy7
Taking a few moments to recognize some outstanding work from our lab: two graduate students had their abstract titled "3D Holotomographic Imaging of Live Cells to Characterize Endothelialization" accepted for the @BMESociety annual meeting. 🎉🧪More accomplishments TBA soon!
Important report from @isth SSC about the state of basic research in thrombosis & hemostasis. This figure is disturbing: clinical abstracts in gray; basic science in red. Thrombosis remains a leading cause of disability & death worldwide. Not good if basic science is contracting!
New article: TF pathway of blood #coagulation is complex network controlled by multiple feedback loops that coalesce around thrombin. Lakshmanan et al @OHSUNews predicts & experimentally validates that TFPI modifies the role of FXI in thrombin generation. bit.ly/39mCRoG
This predication was experimentally validated using #thrombin generation assays with function blocking antibodies against TFPI and plasmas depleted of FXI.
This work should serve as a template for predicting novel biochemical interactions in thrombosis and hemostasis
positive feedback of blood coagulation factor XI (#FXI) activation by thrombin can be abolished by selectively eliminating the inhibitory function of tissue factor pathway inhibitor (#TFPI) using a computational model in #Python.
New Publication from @JurneyLab and collaborators @OHSU_BME@VandyBME
Revised model of the tissue factor pathway of thrombin generation: Role of the feedback activation of FXI onlinelibrary.wiley.com/doi/10.1111/jt…
Demonstration of the complimentary powers of computation and experiment in
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