The Shah Lab @LabShah
This is the web presence of the Shah lab. We fight tuberculosis by understanding the people who are at highest risk for developing it. shahlab.weebly.com Seattle, WA Joined September 2019-
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Followers214
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Following235
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The Shah Lab retweeted
Diminished Mycobacterium tuberculosis-specific T cell responses during pregnancy in women with HIV and receiving isoniazid preventive therapy ✅ Just Accepted ✍️ @LabShah 🔗 bit.ly/4jKd75B
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The Shah Lab retweeted
"The integrated stress response (ISR) enables cells to cope with insults...we identify time- and dose-dependent gene expression modules, with ATF4...rerouting carbon utilization towards amino acid production & away from the TCA cycle and FA synthesis." nature.com/articles/s4146…
Really cool paper on the effects of SCFA with macrophage inflammation.
Glad to share our recent work on the reprogramming of resolving monocytes capable of inter-cellular propagation of immune-homeostasis and reducing atherosclerosis. ahajournals.org/doi/10.1161/CI…
The Shah Lab retweeted
Glad to share our recent work on the reprogramming of resolving monocytes capable of inter-cellular propagation of immune-homeostasis and reducing atherosclerosis. ahajournals.org/doi/10.1161/CI…
@SoleimanpourLab @JinLi33877470 Welcome to the proteostasis club, Scott!
The Shah Lab retweeted
New study from us! 😀 Using quantitative proteomics led by @JinLi33877470, we found evidence for mitochondrial protein misfolding in human islets in T2D that led us on our first journey into proteostasis! Feedback desired and appreciated! biorxiv.org/content/10.110…
We are strangely moved to be back home in Chicago after so long. Looking forward to a great time reconnecting with colleagues at #AAI2024
The Shah Lab retweeted
Interested in doing a postdoc in Seattle? Join us May 7 for Seattle DROP, a virtual biomedical postdoc recruitment event. The first 250 US registrants enjoy lunch via delivery voucher! Underrepresented candidates are esp encouraged to attend. Register: bit.ly/seattledrop
The Shah Lab retweeted
Time to ditch @BioRender? I had no idea they were claiming copyright to the figures we make with it, even after we pay for use of the service.
@DaniBeckman @dava_keavney @nquinoneso Like, come tf on @BioRender biorender.com/academic-licen…
We found that a tuberculosis resistance protein protects from alveolar macrophage necrosis by controlling lipid accumulation and the integrated stress response. @NatureMicrobiol #TB rdcu.be/dCnCc
The Shah Lab retweeted
Take a look at our latest TB article by @LabShah showing the mechanistic basis for why TOLLIP deficiencies increase severity of Mycobacterium tuberculosis infection nature.com/articles/s4156…
@SaraSuliman13 @NatureMicrobiol Most definitely!
@slkshoes congratulations -- this is a really cool study and i'm glad to see it in the wild finally
@TheBrysonLab We've got a publication coming out soon that uses this technique quite a bit.😎
@a_mishra1 @TheBrysonLab Sure. We followed the protocols from Vermeleulen et al, which I've linked below. The appropriate doses also varied somewhat on type of macrophage used sciencedirect.com/science/articl…
The Shah Lab retweeted
Are you on the West Coast? Do you work on TB? Come to the PacTB meeting in May! seatrac.uw.edu/training/pactb
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