Jason Mercer @MercerLab
Pox Virologist and Systems Biologist, Virus Cell Biology Lab, @IMIBirmingham @UoBbiosciences birmingham.ac.uk/staff/profiles… Birmingham, England Joined October 2016-
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@MahadiFX0 Ahhhh, the good old days of bare knuckle boxing in high school gym class 😅
This points to a direct, regulated interaction between viral proteins and the host lipidation machinery. Thank you to co-authors @ayakimovich, @MercerLab and Ingo Drexler
🔥 Open postdoc position in human inflammation-driven control of infection! Join me at the University of Geneva, Switzerland this summer as I’m moving my Wellcome-funded research activity to the Department of Microbiology and Molecular Medicine! Please RT (1/5)
Congratulations to @m_krause0206 for her paper just out in @JCellBiol! See her twittorial below and thanks to all the great collaborations 🙏
The main story of my PhD research project is finally out in @JCellBiol today! rupress.org/jcb/article/22… We were looking at how Vaccinia virus circumvents host immunity by disabling the autophagy machinery through depletion of sequestome-like receptors (SLRs). For a 🧵see below:
Paper out with former @LMCB_UCL colleagues @SamolejJ and @MercerLab Cardiac glycosides inhibit early and late vaccinia virus protein expression - go.shr.lc/3J1e2NC
And another one for @SamolejJ! Here he shows how cardiac glycosides (think toad venom) inhibit poxvirus infection. Just out in JGV @MicrobioSoc microbiologyresearch.org/content/journa… Great working with @StrangVirusLab and @EM__Ian once again!!
Bisbenzimide compounds inhibit replication of prototype and pandemic potential poxviruses! @SamolejJ has extended our understanding of these novel poxvirus inhibitors @StrangVirusLab @MercerLab @ayakimovich mpox work by @cvr_crush journals.asm.org/doi/10.1128/sp…
Congratulations to @SamolejJ who shows that bisbenzimides block replication of prototype (vaccinia) and pandemic potential (mpox) poxviruses! Just out in @JournalSpectrum journals.asm.org/doi/10.1128/sp… Excellent collaboration with @StrangVirusLab @CVRinfo @lifearc1 and @ayakimovich
Really happy to see this work out and peer reviewed. Thanks a lot to everyone involved. Here is a happy bleb to entice you into reading our deep dive into vaccinia virus binding!
Congratulations to @laurapokorny who shows that virus binding proteins aren’t just for binding! Just out in @emboreports Thanks to all who contributed! @JemimaBurden @yorgomodis @D4V1D_4 Becky Bamford,Kendra Leigh,Pooja Sridhar,Timothy Knowles embopress.org/doi/full/10.10…
Congratulations to @laurapokorny who shows that virus binding proteins aren’t just for binding! Just out in @emboreports Thanks to all who contributed! @JemimaBurden @yorgomodis @D4V1D_4 Becky Bamford,Kendra Leigh,Pooja Sridhar,Timothy Knowles embopress.org/doi/full/10.10…
Today we opened the wonderful play ship for the @HanburySchool children in Leo’s memory. 💚 All made possible by resources, work and enthusiasm of our friends, community and the school. 😍 We are grateful Leo’s ship will bring years of fun to the kids. 🙏
Children at Hanbury C of E First School celebrated the launch of a spectacular new play area, built to celebrate the life of one of their beloved classmates. HFS Leo was “launched” today by Leo Mercer’s family. hanbury.eschools.co.uk/web/play_area_…
💥 Out now @ScienceMagazine. @DanielHFisch solves the mystery of bystander cell protection during infection. An exciting mechanism, cells are so smart! PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection | Science science.org/doi/full/10.11…
We miss you Leo at Christmas and every day. 🎄💚
The @WorcCathedral Christmas Tree Festival features trees decorated by local schools & other organisations. Ours celebrates the life of Leo and aims to reflect things he loved; nature, the colour green and the great outdoors. Admission is free until 8 Jan: tinyurl.com/TreeFest22
As expected, the quality of science presented remained high also on the 2nd day. Many thanks to @MercerLab (@IMIBirmingham, @UoBbiosciences), @YamauchiLab (@ETH_en), Serge Mostowy & Ana Lopez Jimenez (both @MostowyLab, @LSHTM) for being with us this morning. #MLIDS @CASUSscience
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