The ADC land grab just found a new frontier.
@JNJNews is paying $1B for #FireflyBio's DAC platform — same antibody precision, but the payload degrades proteins instead of poisoning cells.
oncodaily.com/techology/jj51…
. @Roche is betting big on BTK degradation🧬
Its up-to-$2.3B @Nurix_Tx deal brings bexobrutideg, an oral BTK degrader, closer to Phase III CLL testing after early data showed an 80.9% ORR in heavily pre-treated CLL.
Read more: oncodaily.com/techology/nuri…
Don’t take yourself too seriously: Michael Bailey
The best advice one can receive! Very motivating and inspirational talk with the CEO of AVEO Oncology.
Thank you very much, Michael! It was really a great pleasure.
oncodaily.com/magazine/micha…@AVEOOncology@oncodaily@oncodailyGU @oncodailyBio
🩸One blood draw. 10 cancers.
@US_FDA just granted Breakthrough Device Designation to SPOT-MAS 10 from @GeneSolutions
that detects cancer signals across 10 types, including 5 with no standard screening today. 🧬
oncodaily.com/techology/gene…
🧬 10 oncology biotechs to watch at #ASCO26:
From AI foundation models to RAS(ON) inhibitors & cancer vaccines. Which modality defines the next decade?
oncodaily.com/techology/asco…
🧬 Big pharma is racing to buy ADC companies.
But the real prize isn't the drug. It's the linker platform.
They're not buying the fish 🐟 they're buying the boat⛵
oncodaily.com/techology/adc5…
We are incredibly proud to share that the FDA has approved Signatera™ CDx as a companion diagnostic for use with adjuvant atezolizumab (Tecentriq®) in muscle-invasive bladder cancer. This is the first FDA-approved molecular residual disease (MRD) companion diagnostic in history – a milestone to celebrate on many levels!
Today’s news speaks volumes to the transformation well underway in MRD-guided cancer care. Signatera has become a cornerstone of precision oncology, with extensive support from more than 185 peer-reviewed publications.
By detecting microscopic amounts of tumor DNA in the blood, Signatera can identify MRD earlier than standard tools, allowing physicians to intervene sooner and improve outcomes for patients. Just as importantly, Signatera can help identify patients who are MRD-negative and may be able to avoid unnecessary therapy and its associated toxicity. Altogether, this has a tremendous impact on the lives of patients and their loved ones.
This approval was supported by the landmark Phase III IMvigor011 study, published in The New England Journal of Medicine, which demonstrated the power of MRD-guided treatment decisions in bladder cancer. We’d like to thank our esteemed collaborators at @Genentech and @Roche, the principal investigators of IMvigor011, and our clinical trial participants for their contributions to this major milestone in cancer care.
Read the full press release here: ow.ly/M0GZ50Z0isa#PrecisionMedicine#Oncology#Natera
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