Ploegh lab @PloeghLab
Student/postdoc run twitter for lab of Hidde Ploegh childrenshospital.org/research/labs/… Joined November 2019-
Tweets14
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Followers128
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Following25
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Likes11
Thank you to our wonderful collaborators for their support @danmucida @victora_lab @SetteLab @timlu @ejalm Twitterless Jim Moon and all the co-authors!
Check out the last paper from the @ploeghlab! Beautiful teamwork between our former PhD student @DjenetBousbaine and former postdoc @ambilate. science.org/doi/10.1126/sc…
In @ScienceMagazine this week, @DjenetBousbaine, @PloeghLab, @ambilate, & al report peptides derived from β-hexosaminidase—a highly conserved enzyme produced by #Bacteroidetes commensals—drives regulatory CD4+CD8αα+ #IEL differentiation in #gut! bit.ly/Sci_abg5645
A conserved Bacteroidetes antigen induces anti-inflammatory intestinal T lymphocytes pubmed.ncbi.nlm.nih.gov/35926021/ Awesome collaboration with far reaching implications. CD4 T cells of a single specificity can recognize a variety of abundant commensals and elicit regulatory responses.
👇👇👇💪💪💪
Very happy to share our new study @ScienceMagazine, showing that members of the Bacteroidetes phylum can induce anti-inflammatory intestinal lymphocytes. Huge shoutout to @DjenetBousbaine who led this work. Brava! 1/ science.org/doi/10.1126/sc…
I am thrilled to share my PhD work @MicrobiologyMit @MITBiology @BostonChildrens out today at @ScienceMagazine. 1/ science.org/doi/10.1126/sc…
In @ScienceMagazine this week, @DjenetBousbaine, @PloeghLab, @ambilate, & al report peptides derived from β-hexosaminidase—a highly conserved enzyme produced by #Bacteroidetes commensals—drives regulatory CD4+CD8αα+ #IEL differentiation in #gut! bit.ly/Sci_abg5645
@ScienceMagazine @DjenetBousbaine @PloeghLab @ambilate Please also be sure to check out the accompanying Perspective by Meera Shenoy & @KochMeghan! bit.ly/Sci_add7145
Cool discovery in @ScienceMagazine that could have implications for #inflammatoryboweldisease. @DjenetBousbaine in @PloeghLab find that an antigen shared by many members of the gut microbiome elicits certain regulatory T cells that suppress inflammation. bit.ly/3zYYfeE.
Nanobodies are amazing tools to noninvasively image specific subsets of immune cells (allowing, for example, monitoring the progress of immunotherapy). Together with @PloeghLab, we wrote a review article @OncologyAdvance on this subject @DanaFarberNews esmoiotech.org/article/S2590-…
Thrilled to share our work on the recognition of commensal-derived antigen by CD4 CD8aa T cells in a transnuclear mouse model developed in our lab. These T cells help to temper harmful immune responses in the gut Stellar work by @DjenetBousbaine @biorxiv biorxiv.org/content/10.110…
The Ploegh Lab is looking to hire a postdoctoral researcher with experience in chemistry--see our posting: chemjobber.blogspot.com/2019/11/postdo… And our new lab website: ploeghlab.com @Chemjobber
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