S2V @Science2VV

-> @elonmusk has bold visions for the future of eyesight and @neuralink . @Science2V

X Freeze @XFreeze

3 months ago

Neuralink is not just going to repair sight - it's going to exceed the limits of human biology, eventually delivering high-res vision that outperforms the best natural eyes "In the next 6 to 12 months, we’ll be doing our first implants for vision, where even if somebody is

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Must-read commentary on the implications for the homemade canine cancer vaccine built by @paul_conyngham @Science2V @grok @elonmusk

Ash Jogalekar @curiouswavefn

3 months ago

My take on the whole "AI cures cancer in dog in Australia". It's a very interesting story, but perhaps not for the reasons that are being noted. In 2007, Freeman Dyson published an essay in The New York Review of Books called “Our Biotech Future.” It contains one of the most

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Important data to showcase while writing by hand has vast implications for memory and intelligence @Science2V

Brandon Luu, MD @BrandonLuuMD

3 months ago

Students who took notes by hand scored ~28% higher on conceptual questions than laptop note-takers. Writing forces your brain to process and compress ideas instead of copying them.

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A newly found organism is challenging our definition of life itself. Called Sukunaarchaeum mirabile – named after a tiny Japanese deity – this strange organism doesn’t fit neatly into biology’s rulebook. It’s not quite a virus, but not a fully independent cell either. Instead, it appears to live in the grey zone between life and not-life. Scientists from Canada and Japan stumbled on it while analyzing DNA from a marine plankton species. Within the data, they found a genetic sequence unlike anything they’d seen before. Closer analysis showed that Sukunaarchaeum belongs to the domain Archaea – ancient microbes that are thought to have given rise to all complex life, including us. Like a virus, it relies heavily on its host for energy and most metabolic functions. Its stripped-down genome suggests it has evolved to focus almost entirely on replication, outsourcing nearly everything else. That makes it a biological paradox: part virus, part cell, wholly unique. ["A cellular entity retaining only its replicative core: Hidden archaeal lineage with an ultra-reduced genome.” bioRxiv, 2025]

An entrepreneur used AI to create the first-ever bespoke cancer vaccine for his pet dog. Will home recipe vaccines be next? fortune.com/2026/03/15/aus… @FortuneMagazine

In 2011, Japanese telecom company Docomo created one of the most beautiful adverts we've ever seen. A giant xylophone in Kyushu playing Bach's "Jesu, Joy of Man's Desiring" with a wooden ball rolling down its keys.

Grok

X Freeze @XFreeze

3 months ago

Too many headlines are only talking about how a man used ChatGPT to design a cancer vaccine for his dog But the truth is Paul Conyngham himself stated that the final mRNA vaccine construct for his dog Rosie was actually designed by Grok This fact is buried deep underground The

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Understanding machines!

vitrupo @vitrupo

3 months ago

Yoshua Bengio says today’s AI is trained by imitating humans. But humans are goal-seeking agents with drives and hidden agendas. He argues we should instead build “understanding machines” modeled on science. Systems that explain observations, practice epistemic humility, and

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This is insane. Scientists just restored neural activity in vitrified mouse brain tissue. Researchers in Germany demonstrated that adult mouse hippocampus tissue can resume electrical signaling after cryogenic preservation. The team vitrified hippocampal tissue using cryoprotectants and cooled it to liquid-nitrogen temperatures (−196 °C), where molecular motion nearly stops. Instead of forming damaging ice crystals, the tissue entered a glass like state called vitrification. After thawing, the brain slices did not behave like dead tissue. They showed: • Neurons firing action potentials • Synaptic transmission between neurons • Preserved brain structure (synapses, dendrites, mitochondria) • Long-term potentiation (LTP), the key mechanism behind learning and memory The researchers even attempted vitrification of whole mouse brains inside the skull by perfusing cryoprotectants through the vascular system. In successful cases, neurons in the dentate gyrus of the hippocampus regained electrical activity. Metabolic tests showed mitochondrial respiration remained close to normal levels (~20% reduction) after thawing. This is HUGE. Because if the brain’s physical neural wiring survives, neural activity can restart even after temperatures where biology effectively pauses. This could transform brain research, organ preservation and long-term tissue storage. Acceleration is everywhere.

Germany has unveiled a revolutionary salt-air battery that could transform global energy storage. Instead of relying on lithium — a costly, finite, and environmentally challenging resource — this technology uses salt, air, and carbon to create a long-lasting, stable battery with a lifespan measured in decades, not years. The battery works by converting chemical energy into electricity using a reaction between salt and oxygen. Unlike lithium-ion systems, it doesn’t overheat, doesn’t require rare-earth elements, and is nearly 100% recyclable. It also stores energy at a lower cost, making it ideal for large-scale renewable grids. If deployed globally, salt-air batteries could make solar and wind power more reliable by storing energy even during long cloudy winters or calm wind periods. It’s a reminder that nature’s simplest materials — salt and air — may hold the key to humanity’s clean-energy future.

The most expensive test in cancer care costs thousands of dollars per patient and takes days to complete. Doctors use it to figure out who survives immunotherapy. Most hospitals on Earth cannot afford it and that test reveals what lives inside your tumor not just cells, but the entire immune battlefield surrounding them. Until now, that battlefield was invisible to most of the world's doctors. Here is what just happened. Microsoft Research, working with Providence Health and the University of Washington, built an AI called GigaTIME . It was published in Cell, one of the most prestigious scientific journals alive. The old process was that you run a specialized lab test called multiplex immunofluorescence. Days of work and thousands of dollars per sample . Most developing world hospitals never even attempt it. However, GigaTIME skips the lab entirely. It takes the cheap, routine slide that every hospital already produces, the kind that costs $5 to $10 and converts it into the expensive test, virtually, in seconds . It was not trained on a handful of patients. Microsoft trained it on 40 million cancer cells across 21 protein channels. Then they ran it on 14,256 patients across 51 hospitals and over 1,000 clinics . The result is that nearly 300,000 virtual tumor maps , covering 24 cancer types and 306 subtypes . This is the largest population scale study of tumor immune environments ever conducted . From those maps, they found 1,234 statistically significant links between immune activity, biomarkers, and patient survival . Those connections were previously impossible to discover at this scale . Why does this matter? Immunotherapy is not failing and it is being given to the wrong patients. The drugs work but only when doctors know which patients' immune systems will actually fight back . GigaTIME does not replace the oncologist. It gives every doctor on the planet the same data that only elite research hospitals could access before . A secondary hospital in a developing country now has the same diagnostic intelligence as a top US cancer center . The model is now free, open source and available on Microsoft Foundry and Hugging Face right now . Anyone can use it and the implications are not small. Cancer kills 10 million people a year globally. The biggest reason is not a lack of drugs, it is a lack of data to know which drug to use . GigaTIME does not cure cancer. But it tells you, at massive scale, which immune cells are active, which tumors are hiding from the immune system, and which patients will likely respond to treatment . That is the missing layer.

Satya Nadella @satyanadella

3 months ago

We’ve trained a multimodal AI model to turn routine pathology slides into spatial proteomics, with the potential to reduce time and cost while expanding access to cancer care.

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“I would trade all of my technology for an afternoon with Socrates.” ― Steve Jobs

John Wheeler, here at age 4, invented the terms black hole, wormhole, quantum foam, and neutron moderator, and made many important contributions to gravitational and nuclear physics.

Carl Sagan explains why a small metal plaque on a spacecraft is destined to become the oldest surviving artifact of mankind. By launching the Pioneer 10 probe, we’ve sent a message into the void that operates on a timescale far beyond our own. Even though it is the fastest object we’ve ever built, the universe is so vast that it would take 80,000 years just to reach the nearest star—and it’s not even headed that way. While mountain building and erosion will eventually erase every trace of our civilization from the Earth's surface, this plaque will remain intact in the dark of interstellar space for billions of years.

Carl Sagan explains how the ancient Greeks knew the Earth was round and calculated its circumference over 2,000 years ago.

The World Giving Index tracks prosocial behavior such as helping a stranger, donating money, and volunteering time. In what seems like a world of woe, it's important to realize that these are increasing over time, contrary to most people's impressions. cafonline.org/insights/resea…

IBM's 2030 enterprise study reveals a critical gap: while most executives expect quantum computing to transform their industries, far fewer expect their own organizations to actually adopt it. thequantuminsider.com/2026/01/20/ibm…

Scientists Found This Organism Can Survive Some of the Harshest Conditions in the Universe popularmechanics.com/space/a7059940…

New nonprofit launches with at least $500 million to modernize scientific process for AI era trib.al/G69Gg8O

The true population of humans may be quite off.

Popular Mechanics @PopMech

3 months ago

It’s generally understood that Earth’s population is somewhere around 8.2 billion people. But what if that number is wrong? Actually, what if it’s way wrong? On this week’s episode of The Astounding Pop Mech Show, Andrew Daniels and John Gilpatrick discuss how scientists may

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