Zlatic Lab @ZlaticLab
Deciphering circuit mechanisms of learning and action-selection at @MRC_LMB www2.mrc-lmb.cam.ac.uk/group-leaders/… Joined December 2020-
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Zlatic Lab retweeted
Scientists have generated the first complete map of the brain of a small insect. The map shows all 3,016 neurons and 548,000 synapses tightly packed in a young fruit fly's brain, which is smaller than a poppy seed go.nature.com/3ZTAU8q
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Zlatic Lab retweeted
We’ve generated a synapse-resolution map of an insect brain, includes 3016 neurons and half a million synaptic sites! Out today in Science science.org/doi/10.1126/sc… Summary below and in @bpedigod’s thread. @ZlaticLab, @albertcardona, @neuro_data, Carey Priebe, and many others
Zlatic Lab retweeted
How does the brain work? 🧠 Today, scientists reveal the first complete brain wiring map in a relatively complex animal. The map can help understand how signals travel through the brain to drive behaviour and learning 👇 @PDN_Cambridge @CamZoology @MRC_LMB
Zlatic Lab retweeted
Our work studying the connectome of an insect brain, that of a Drosophila larva, is out today in Science! science.org/doi/10.1126/sc… Some highlights below and in @WindingMichael’s thread. Work with @neuro_data, Carey Priebe, @albertcardona, @ZlaticLab, and many others.
@WindingMichael @BPedigo @albertcardona @neuro_data @BPedigod thread ;)
Zlatic Lab retweeted
More coverage of @neuro_data and @ZlaticLab's groundbreaking work, out today in @ScienceMagazine.
The first wiring map of an insect's brain hints at incredible complexity npr.org/sections/healt…
@behaviOrganisms @ScienceMagazine @WindingMichael @bpedigod @MRC_LMB @Cambridge_Uni @HopkinsEngineer @JHUBME Thank you 😊
👋 It is out! Our joint effort to create a complete synaptic connectome of Drosophila larval brain came true and is published in @ScienceMagazine: science.org/doi/10.1126/sc… Amazing work by @WindingMichael, @bpedigod + colleagues from @MRC_LMB @Cambridge_Uni @HopkinsEngineer @JHUBME
Zlatic Lab retweeted
ok. i've peaked. it's all downhill from here. i was interviewed as the "expert not involved in the study" by GIZMODO (!!😍!!) on the new larval connectome paper, out today in science from @albertcardona, @ZlaticLab, and colleagues. amazing work!! gizmodo.com/first-complete…
The complete synaptic-resolution connectome comprises 3016 neurons and 548,000 synapses. We believe that this complete brain connectome will be a lasting reference study, providing a basis for a multitude of theoretical and experimental studies of brain function in general🧠
We would like to cordially thank to @albertcardona, Carey Priebe, @jovo, Volker Hartenstein, Richard Fetter and their labs and @HHMIJanelia for all the support on this journey 🙏
Good luck @WindingMichael 🥳 We'll miss you...
I am starting my own research group at @TheCrick Institute in London! We will be investigating how neuronal circuits in the brain drive social interactions between animals. I have an immediate opening for a PhD student, apply by 22 March! crick.ac.uk/research/labs/…
3/3 In addition, our system will enable rapid screening for neurons and circuits that underpin different forms of learning and also has the potential to drive future research in larval taxis, decision-making, and spatial navigation and #memory.
2/3 This stimulation is delivered automatically with high temporal precision and is controlled in either open- or closed-loop. Using this approach, we show for the first time that Drosophila larvae can perform classical #conditioning with no overlap between sensory stimuli.
📢Did you know that we have developed a high throughput training system that allows real-time behaviour detection of freely moving larvae (up to 16) with targeted opto- and #thermogenetic stimulation of tracked animals in #Drosophila? elifesciences.org/articles/70015 1/3🧵
Zlatic Lab retweeted
Over 50,000 annotations have been added to the connectome by the FlyWire community! This APL neuron, tagged by @mwpleijzier @zhihaozheng, is 20x longer than a fly's whole body and is the longest cell in the brain. Proofread by labs of @gsxej @MurthyLab @sebastianseung
Zlatic Lab retweeted
Sneak peek: We will soon be releasing a complete insect brain connectome! With both brain hemispheres mapped, we can study how the left and right sides of the brain communicate #Drosophila #neuroscience
👉 Our new preprint is out on #BioRxiv It is a comprehensive work between our lab, @albertcardona lab and our collaborators, with our talented postdoc @WindingMichael as a co-first author and also one of the coresponding authors 🥳
Check out our new preprint: the complete #connectome of the entire #Drosophila larval brain, with all inputs and all outputs, and a comprehensive analysis of feedforward and feedback pathways across both brain hemispheres #Neuroscience biorxiv.org/content/10.110…
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