Human BioMolecular Atlas Program (HuBMAP) @_hubmap
an NIH-funded consortium of scientists developing an open, global framework for comprehensively mapping the human body at a cellular resolution. hubmapconsortium.org Joined March 2019-
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Human BioMolecular Atlas Program (HuBMAP) retweeted
NEWS: NIH research establishes new framework for the role of senescence in aging. Read the full story ➡️ nih.gov/news-events/ne…
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FOXJ1 - orange in epithelium, motile ciliated cells SCGB3A2 - pink - lung epithelial cells and submucosal glands SFTPB - pulmonary surfactant protein MUC5AC - bright blue - gel-forming glycoprotein in the lungs MUC5B - turquoise - gel-forming mucin protein
Lung - Airway Epithelium and Submucosal Gland and Duct PTPRC - CD45 - Orange - immune cells PECAM1 - CD31 - Green - endothelial cells KRT5 - Yellow - basal epithelial cells ACTA2 - White - smooth muscle cells
follicles - red and blue, luteinizing cells - pink, extracellular matrix - purple, green, white, vessels - yellow and orange
Does this CODEX image of an ovary send you ova the moon? This egg-citing image was made by NIH funded #_HuBMAP scientists @UPenn & @LurieChildren's, using antibodies specific to cell types found in the ovary to show the spatial relationships within. Ova it? Never!!!!
Photo credit - UPenn & Lurie Children’s (O’Neill, Kim, Laronda)
Not to be an ovary-achiever, but this CODEX image of oocytes in a healthy human ovary made by scientists at @UPenn & @LurieChildren’s is egg-straordinary! Images like this prove researchers aren’t just follicle-ing around! 😉
Green – oocytes, Pink – extracellular matrix, Cyan – vessels, Blue and Yellow – epithelial cells
Do you have the intestinal fortitude to check out your viscera? Then follow your gut instincts and digest this CODEX image of a healthy colon from John Hickey when he was at the of the Nolan Lab Stanford. We hope it bowels you over as much as us!
Red - podocytes, green - endothelial cells, yellow - smooth muscle cels and arterioles, cyan - thick ascending limb tubules, blue - proximal tubules, brown - distal convoluted tubules
Pi day just passed, so you know what that means! It's time for a slice of kidney pi(e), and that's a renal treat! This CODEX image of a kidney pi slice was made by #hubmap researchers Drs. Tarek Ashkar & Sanjay Jain @wustl, and we're not being irrational!
Stroma and ECM - green and blue; Endothelium - red, white, magenta, and cyan; Macrophages - yellow
Not to be ovary-serious, but this CODEX image of an ovary made by HuBMAP researchers Elizabeth Tsui, Hannah McDowell (Laronda lab at @NUFeinbergMed) & Alex Cabrera, Jean Rosario (O'Neill lab @PennMedicine) is egg-squiste! Hopefully, it fertilizes and catalyzesyour imagination!
DYK that bone marrow makes your blood cells? To get to the meat of the matter, come see this MIBI-TOF image visualized in CellTune, a software that classified the cells across the tissue section. Not to be too bloody marrow-minded, but this CellTune software sings! 😊
Yellow – lipid droplets, green – natural killer cells, light blue – endothelial cells, magenta – smooth muscle cells, orange – erythroid cell precursors, white – type I collagen, dark blue – hematopoietic stem cells
Decided to see this mass spec image of the decidua from MikeAngeloLab @stanford? Excellent choice! The decidua lines the uterus during pregnancy & forms the placenta. This image also captures fetal cells within & around maternal spiral arteries because we always deliver for you!
Nuclei - blue, Immune cells - green, basement membrane - red, cardiomyocyte membranes - yellow, smooth muscle cells - cyan, endothelial cells - magenta
To beat or not to beat that is the question Whether 'tis nobler in the mind to skip a beat Or pulsate with joy over the heartistry Of an image made by @GEHealthCare Using CellDIVE to see inner workings Of the heart is work not done in vein Tis a consummation devoutly to be wish'd
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