Order_of_the_Dolphin @dolphin_order
I Like. I Hyperfocus. I Post. Joined May 2020-
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I think this is why I am such a fanboy of Shuglin, and those like him, as he valued human subjective experience above all. Although the mechanisms are fascinating, he ultimately put the experience itself centre stage, treating the mind as a laboratory. Pretty wild stuff.
They each have their own distinct flavour. There is real value in this beyond 'you're just on drugs' as these compounds bring into focus, be it exaggerated, or altered in some way, those underlying processes that shape our conscious experience, and as an extention, our behaviour
One of the most insightful things you can aquire from trying various different psychoactives is a direct felt experience of how different neurotransmitters, receptor sites and molecular mechanisms shape the conscious experience. Be it emotional, behavioural, or physiological.
@aestheticprimal Obviously MDMA isnt serotonin, but this effect is a consequence of increased synaptic serotonin. All entactogens share this mechanism regardless of chemical structure.
@aestheticprimal Yes, it's subtype specific. Primarily (in the brain) it functions as an inhibitory neurotransmitter, but there are certain subtypes particularly 5-HT3 which are excitatory. Hightened anxiety and panic are linked to this subtype with overactivation. 5-HT2A is also excitatory.
@aestheticprimal There are also countless studies demonstrating lower impulsivity in people with higher (not excessive) serotonin levels. It's an inhibitory neurotransmitter for a reason.
@aestheticprimal These are well understood mechanisms. Probably the most remarkable study showing this is octopuses given MDMA. Usually they are extremely territorial and voilent towards other octopuses in their space. When given MDMA through 5-HT1A activation/endorphin release, they hug.
@aestheticprimal Now take someone at the bottom, not happy in their situation, and artificially raise their serotonin with a daily dose of SSRI. Instead of wanting to better the situation they find themselves in, they become content in this existence.
@aestheticprimal This is why you see higher levels of serotonin in leaders. Your brain is applying the breaks. You've achieved dominance. You can ease up now. Less approval seeking, less risk taking, less impulsivity, less violence. All important on the climb, but risky when you are in charge.
@TheManlet_King America has higher rates of male pattern baldness. Just saying.
@doctormorphh Thoughts on phenylpropylaminopentane instead of d-amphetamine?
The Song that made Oliver Tree ! Rest in peace man💔🕊️
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HMS Medusa. Built in Poole in 1943 by RA Newman, Medusa is now the last of 464 vessels of her class that is in original and seagoing condition.
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@BowTiedHRT @kalospepgod Do you have ADHD?
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🪽💜✨💮🌬�... @MeraltrTr
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🪽💜✨💮🌬�... @MeraltrTr
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