UFO-Z☀️ @ufobtc27
Tech Cultist|AI@█| Brain 🧠Computer @orama__desci|PhD in Condensed Matter Physics t.me/Pythia_DAO Brain Computer Interface🧠 Joined November 2021-
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Artificial intelligence is not replacing human intuition in maths and physics, but reimagining how questions are asked, explored and understood go.nature.com/4vG4Vsl
Boltzmann generators go big: scalable equilibrium sampling for materials Predicting whether a crystal phase is stable, or computing its free energy, usually means running molecular dynamics for a long time. The problem is that MD explores configuration space one step at a time, so consecutive snapshots are correlated and the system mixes slowly. Boltzmann Generators offered a clever alternative: train a normalizing flow to map random noise straight onto the Boltzmann distribution, giving uncorrelated equilibrium samples in one shot, plus free energies through reweighting. The catch was scale. Earlier BGs maxed out around 500 atoms, with poor sampling efficiency and training runs approaching a full GPU-year, slower than the MD they were meant to replace. Schebek, Noé and Rogal fix this with a clean idea: stop modeling the whole configuration at once and learn from local atomic environments instead. They pair augmented coupling flows with a graph neural network that builds per-particle embeddings from each atom's neighborhood. By modeling displacements from the ideal lattice rather than absolute positions, the input stays size-independent, so a model trained on a few hundred atoms transfers directly to systems above 1000 atoms. Scaling becomes linear rather than quadratic, and training needs only the energy function, no MD samples. The payoff is large. For mW ice, a global BG needed over 330 GPU days and reached effective sample sizes around 0.2%, while the local model converges in about 4 GPU days and pushes efficiency up by an order of magnitude. It reproduces radial distribution functions and free energies that match MD to within 10^-3 kBT per particle, resolving tiny phase-stability differences in Lennard-Jones crystals, water ice, and the silicon phase diagram. Conditioning on temperature, pressure, and interaction parameters lets one model cover a whole family of materials. The real lever is cost. A trained flow needs only tens of thousands of energy evaluations for a large cell, against tens of millions for standard MD free energy methods, and that gap widens sharply with expensive machine-learned interatomic potentials. In materials development, energy storage, and catalysis, this means screening phase stability and thermodynamics at realistic system sizes without paying the usual simulation tax. Paper: Schebek et al., Nature Communications (2026) — CC BY 4.0 | doi.org/10.1038/s41467…
Mark Rocket Science @SpaceX 基本是热流体力学,燃烧科学 这块多尺度 CFD ,空天凝聚态物理还有很多大空间可为!
Yann LeCun décrit un monde qui l'a enfanté, et ce monde est en train de mourir. Le modèle qu'il défend est celui du XXe siècle. La recherche fondamentale d'un côté (universités, PhD, papiers), l'application industrielle de l'autre, des décennies plus tard. Une chaîne longue, lente, découplée. La découverte en amont, la valeur en aval, et vingt ans entre les deux. Elon a prouvé l'inverse. Quand l'ingénierie et la recherche sont totalement intriquées, quand tu pars d'un problème réel à résoudre et pas d'un papier à publier, tu vas infiniment plus vite. SpaceX, Tesla, Neuralink ne sont pas des applications de la recherche académique, ce sont des labos de recherche qui se trouvent être aussi les boîtes les plus innovantes du monde. Et la vérité que personne n'ose dire, c'est que l'écrasante majorité des papiers ne créent aucune valeur. Des gens qui publient pour publier, optimisés pour la citation et pas pour le réel. L'alignement académique récompense le statut. L'alignement capitalistique récompense une seule chose : que ça marche, vraiment, dans le monde. C'est exactement le point de Thiel. Historiquement, les génies créaient une valeur immense et n'en captaient presque rien, parce qu'ils étaient déconnectés de tout véhicule capable de la capturer. Créer de la valeur et capturer de la valeur sont deux choses distinctes, et l'académie a passé un siècle à exceller dans la première en abandonnant la seconde. Dimon le dit à sa façon : Elon est notre Einstein. Sauf que cet Einstein-là n'a pas eu besoin de l'université pour produire ses percées. Il a eu besoin d'un problème, d'une équipe d'ingénieurs et d'un alignement commercial brutal. Ses breakthroughs dans le spatial, l'automobile et le cerveau ont créé plus de valeur réelle que tout le système académique réuni sur vingt ans. Et avec l'IA, le basculement s'accélère. La valeur du diplôme s'effondre, celle de l'école aussi, parce que l'intuition d'ingénierie branchée sur le réel devient le seul moteur qui compte. LeCun n'a juste pas remarqué que le monde qui l'a fait roi est déjà derrière nous.
@JohnProperBTC @Xnarkycritic @DavidSacks This is targeted R&D with a clear (commercial) purpose. We're talking about basic research here. The kind of federally-funded basic research done 5, 10, or 20 years ago in universities that Elon's projects rely on. The kind of federally-funded research projects that every
@brivael The world changed a lot already Tra Sci Paradigm is shifting
World Labs CEO Dr. Fei-Fei Li: "The world is not made of words." "Language models have given machines an extraordinary command of concepts, vocabulary, and reasoning, but the physical world, virtual or real, runs on a different substrate." "Where language models learn the statistical structure of text, world models learn the statistical structure of space and time: how light falls on a surface, how a garden looks from an angle no camera has captured, how objects respond to force and follow the laws of physics." "Language gave machines a way to talk about that world. World models are how machines will finally come to understand, imagine, reason and interact with it." Full piece: drfeifei.substack.com/p/a-functional…
A new study suggests that motion of #BiomolecularCondensates is different from that of colloidal particles. Externally-controlled dynamic states, such as condensate motion, lead to polarization and dipole force fields. 🔗 go.aps.org/4x8sds4
Fen Cun @cun_fen28668
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saydul islam @isaydul3
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salama @salama5048
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Tigris 会讲课教�... @tig88411109
72K Followers 317 Following Fund partner & Professor (CFA), 30 yrs in macro & tech. Longform on AI, semis, cycles. Buy-side mindset: Facts cheap, Interpretation expensive. 中文短评互动拆逻辑.
tina.in.boca @Boca_Tina
20K Followers 49 Following Starship engineer at spacex working in beautiful Boca Chica 🚀 sometimes u just gotta shout into the void!!!!!
普达特 @Predator_fund
32K Followers 748 Following Predator Quantitative Trading System Developer. 区块链底层技术开发,合约交易为生;“村头CBD社区”创始人. 社群:https://t.co/fUjvAaTmXZ(需申请); 油管:https://t.co/2tq5CAlRcL
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Garrett @GarrettBullish
55K Followers 394 Following macro, crypto, stocks and everything that moves them. https://t.co/7BH7bkvRbJ
Wilming ZHOU @wilmingzhou
402 Followers 934 Following Coder | Startup owner | 密码学/CS双硕士 | 十二年AI与通信行业创业经历、拿过上市公司和一线基金数亿元投资 | 分享创业、技术、营销经历和心得。 Founder of https://t.co/oE5x8Nd1Mx
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Daniel Lemire @lemire
36K Followers 2K Following Software performance expert. Ranked in the top 2% of scientists globally (Stanford/Elsevier 2025) and among GitHub's top 1000 developers. Father, husband.
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114K Followers 61K Following Riding the Bitcoin wave|| Crypto exposure⚡|| Web3 Growth|| Marketing that delivers real impact🚀|| DM for Business📩
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6K Followers 7K Following ● Love all ; don't skip a soul ● Don't be so quick to judge people See You At The Top
Jessica Young @JessicaMetaEra
3K Followers 665 Following AI & Crytpo @SF, NYC & HK|CEO @MetaEraCN | Advisor @Bakkt | Personal views, not company opinions. Interview solely represents the speakers’ views.
gccofficial @GCCofCommons
6K Followers 635 Following The 1st Chinese Non-Profit Crypto Foundation – We Support and Fund Public Goods Projects We Believe In! 🦋
JY🐧🎒 @JYdmnLFG
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Prof. Dr. Sezgin Bak�... @SezginBakirdere
6K Followers 298 Following Scientist (YTÜ), Bakırdere Research Group, Member of TÜBA, Al. Member of GYA, Fellow of Royal Society of Chemistry, METU-Parlar, Secretary General of TCS, IUPAC
贝塔酱 @Walden779
11K Followers 396 Following 📈 US Stocks & Crypto | 🏋️Fitness | 💜INTJ 170| 🧑🎓JHU| lifelong learner |Long $BTC |平平无奇的交易员
National Academy of S... @theNASciences
59K Followers 1K Following As advisors to the nation, we recognize and advance outstanding science for the benefit of society. Journals: @PNASNexus, @PNASNews | President: @Marcia4Science
OpenAI @OpenAI
4.9M Followers 4 Following OpenAI’s mission is to ensure that artificial general intelligence benefits all of humanity. We’re hiring: https://t.co/dJGr6LgzPA
Weijie Su @weijie444
13K Followers 499 Following Researcher @OpenAI, Professor @Wharton, CS, Math @Penn, coDir PRiML, PhD @Stanford
政经鲁社长 @xzzzjpl
686K Followers 331 Following 原“中日政经评论”,一个中间偏右的时政评论家。 付费提问:https://t.co/WlmcbdgMO4 油管加会员链接:https://t.co/B9cQ4FiL8f 国内加会员链接:https://t.co/j3uNCxlDKR 投稿信箱(仅供投稿,咨询勿扰:[email protected]
angel @angeldot_
99K Followers 1K Following 26 | Tech Lead Accesia +100K ARR | AI, automation & startups | growth @aiscwork
168X @168X_Fortune
16K Followers 28 Following 168X is where frontier tech meets capital. Hosted by Mr. Z @168MrZ & Victor @vcmktasa Subscribe now: https://t.co/puoVwpUEZX | https://t.co/QuBpgVWXhJ
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tao terrence @terrence_tao
6K Followers 1 Following Tao's my name and math is my thing:) I could say my greatest quality is that I have my own theorem, you know the green-tao theorem, everyone's heard of that:)
Marc Andreessen 🇺�... @pmarca
3.9M Followers 31K Following You’re not talking to someone who woke up a loser. That loser attitude, that loser premise makes no sense to me.
snowboat @snowboat84
6K Followers 2K Following PhD in Astrophysics → AI Founder. Building in public: indie AI tools & tech rants 每天分享海外华人开发者真实吐槽 📚 https://t.co/WLorXOMLnl 📝 https://t.co/OpMO1d0Yyi 🎬 https://t.co/nJ8zVtlSY4
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27K Followers 5K Following 跟CZ互怼过的男人,专业投资加密圈+外汇黄金11年,K线技术教学,打造推特个人IP流量变现,每月可拿马斯克工资。孵化币安广场、抖音、小红书、微博等博主。另有EA软件出售AI量化全自动化24小时跑,月化达20-40%。请尊重知识付费,非诚勿扰!
Serenity @aleabitoreddit
850K Followers 174 Following I only use X, beware of imposters. AI/Semi Supply Chain Analyst Not investment advice, DYODD. Now publishing free research on AI chokepoints.
CX330D⛰️ @CX330_D
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Prof. Nikolai Slavov @slavov_n
42K Followers 266 Following Mentor, scientist & engineer. Director of @ParallelSqTech. Having fun in @SlavovLab with single-cell proteomics & ribosomes. Organizer of @SCP_meeting
Phoenix Yin @Phoenixyin13
10K Followers 1K Following 🇺🇸 04美本 | 计算机科学&认知科学 ⚙️AI, cognition, crypto, and the future of intelligence. ✨相信好奇心驱动。相信人永远可塑。
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17K Followers 31 Following 「欢迎( ̄O ̄)ノ常来看看」 免责声明: 工具类推文“仅供学习及合法使用,非法使用后果自负” 且所有推文均不是投资建议
Rocky📈 @RockyMsx
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Yi He @heyibinance
610K Followers 1K Following Co-Founder & Chief Customer Service Officer @Binance, Holder of #BNB
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BS Kol Club @BSKolClub
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