Warren Togami @wtogami

One of the things you see all the time in long covid is how patients go to the doctors, the doctors order CBC, CRP, etc, and say there is nothing wrong with the patient. Patient complains but is mostly dismissed because the labs don't show anything. Despite going into psychosis six weeks after my infection, most doctors didn't think there was anything wrong with me. When I came out of the hospital, I had incredible brain fog, almost like I was drunk. It was so bad I sold my car as I couldn't imagine driving it again. Walking seemed weird to me, hand eye coordination was shot, and I felt like I was eating food like a kid, like it was hard to keep my fork straight. Most of the day I had almost some vertigo/disassociation going on with my brain, and even using Excel was hard for me during that period. I would tell doctors all of that, and they would just tell me it was a result of the psychosis, even though I felt absolutely horrific. My lab results at the time looked like this, mostly normal. Cholesterol was a bit high, but other than that, no real red flags. As such, it must be in my head, or so I was told. dropbox.com/scl/fi/tqfi38q…

Republicans are in charge because we promised: to Make America Healthy Again. to start No New Wars, to put people above corporations, to put America above foreign countries, to release the Epstein files, to not spy on citizens, to eliminate fraud, what the hell happened?!

@CovidSolidarit1 Anecdotally a few seemingly normal people told me their brains never fully came back after acute COVID years ago. They are able to hold a job and don't feel sick but feel the permanent loss of 20-30% ability to think. One can't play music anymore. One is far worse at writing.

@DevanaUkraine Daddy why is the sky on fire?

My plan for the antivirals was to hit about 80-90 days and then wind down, which I’m starting to approach. In truth, the jury is still out on whether it worked or not. My labs show something has happened involving IgM and IgG but I’m still not confident with how to interpret it all yet. One of the issues is my RNA seq data is lagged by six weeks. So I haven’t even seen day 42 yet. But that should hopefully come soon. That said, I felt like it would be remiss not to try one anti viral I have avoided over a year - Molnupiravir. Molnupiravir has a bit of a rocky history. It works in a completely different way than most antivirals. GS441524 targets RdRp which makes it so it can’t copy itself. Paxlovid targets Mpro, which means it can’t sub-assemble its sgRNA proteins. The problem with each is that Covid has a proofreading mechanism, nsp14, one that can correct mistakes that are introduced by antivirals. So it’s possible it’s actively working to fix the issue with RdRp and Mpro. Molnupiravir works by lethal mutagenesis. It literally froms a bastardized versions of A and U bases which can then get erroneously incorporated into the virus’ RNA during a copy. These look like regular bases from the nsp14 perspective so it’s unlikely to be able to fix them. After one copy you might get five errors introduced. Now maybe it’s partially disabled or less fit. Next copy five more errors are introduced, and now it’s starting to produce little Seth Brundle mutants that can’t fold proteins or make nsps etc. the errors are random and likely fatal after a few generations. The virus basically dies by error catastrophe. Sounds great, but there are several problems. The first is by definition you are making covid19 clones, and you don’t know if they’ll be defective ones or super ones. In general random errors produce less fit copies, but it’s not impossible the errors can accumulate in a beneficial way. Unlikely though I think. In terms of someone like myself though I’ve been wondering if this might be a good thing. My body has been fighting something for 28 months it can’t seem to get rid. I have no signs of any serious auto immune issues, but what I have is antibody, cytokine, and lymphocyte data that continues to show an active viral antivirus campaign against Covid itself. So the question becomes, how can I break this 28 month stalemate? One way I can imagine if I take one super evolved covid19 clone that’s inside me, likely due to 28 months of specific Duane like immune pressure, and bust it up. So instead of one super clone, maybe I now get 10-20 partially genetically degraded versions instead. Will my immune system have a new shot at them? Let’s see. The other problem is there a non zero chance this can happen with regular cells too. Which is why the medication typically is only taken five days. But in theory if Molnupiravir incorporates into human RNA it’ll eventually break down naturally as long as the DNA hasn’t been changed. Regardless, having seen lots of people who tried it for acute infections with seemingly no ill effects I figured it would be the last antiviral in my test before I start de- stacking meds and give my body a chance to clear itself out from all these meds, which I’m spending about $50-$60 on per day. The fact I haven’t seen clearance yet might not be unexpected In that Madrid study that tested multiple antivirals in immune compromised people, the antiviral courses were ten days but many didn’t officially clear the virus (test negative) for several weeks later all the way out to 100 days before going negative. So it’s possible to stop replication and then spend weeks or months clearing up all the covid viral debris, many of which are still immunogenic. On Monday and Tuesday I’ll do a massive cytokine test, lymphocytes, antibodies, RNA seq #5, and some of the other tests I did at the beginning to bookend some of the results. After that I’ll probably pop the clutch and see what happens.

@DrNeilStone The movie will be about how Russia lost a war of its own choosing despite having multiple Russian agents in the highest positions of the US government.

6 months ago Grok was performing a lot better than Gemini. Gemini was hallucinating hard on both IT and medical topics. Now I'm finding Gemini is frequently finding key relevant details I'm seeking more often than Grok. The hallucinations seem to be better now days too.

@Biff234523 @cb_grl My suspicion has been they needed an easier pathway for approval in the US. Prophylaxis was easier than acute treatment. This is actually fine for the few people who want it because they will end up getting it off-label which would be perfectly legal.

@Biff234523 @cb_grl The no insurance cash price for Xocova in Japan recently was about $380 for me. This order of magnitude is too expensive to be viable as a frequent prophylaxis. Not to mention the drug interactions while better than Paxlovid are still very harsh for persons on CYP3A4 medications.

#SaveStargate

once again, more bullshittery that makes me have to question everything 🤦🥺 Texas lab CEO admits falsifying wastewater test results that concealed E. coli and other pollutant levels for years share.google/szPZwgvIpmEKEt…

In the last month Ukraine has genuinely started winning the war against Russia…

A scientist spent 30 years studying an organ every textbook said was irrelevant. In 2026, two papers in Nature proved she had been right all along. The papers were not written by her. Her name is Noel Rose Mackay. She is a thymic biologist who has studied the thymus since the 1990s, at a time when the field was considered a professional dead end. The thymus is a small immune organ behind the breastbone. By the 1980s, medical consensus had settled: the thymus trains immune cells in childhood, shrinks at puberty, and stops functioning meaningfully in adults. Researching adult thymic function was considered a waste of time and grant funding. Mackay and a small number of colleagues disagreed. They published research throughout the 1990s and 2000s arguing the thymus remained active in adults and that its ongoing T cell production mattered for immune health. The papers were published in smaller journals, cited rarely, and largely ignored by mainstream medicine. For 30 years, clinical practice did not change. Radiologists reading millions of CT scans did not measure thymic health. Oncologists designing immunotherapy did not account for it. No clinical guideline mentioned it. In March 2026, researchers at Mass General Brigham used artificial intelligence to analyse CT scans from over 25,000 adults. The AI found exactly what Mackay had argued for three decades. Adults with healthier thymuses lived longer. 50% lower risk of death from any cause. 63% lower risk of cardiovascular death. 36% lower risk of lung cancer. In cancer patients receiving immunotherapy, stronger thymic health predicted a 37% lower risk of cancer progression and a 44% lower risk of death. Two papers. Published simultaneously in Nature. Covered by Harvard Medical School, Mass General Brigham, and dozens of international outlets. The researchers who wrote them work in artificial intelligence and cancer imaging. They were not thymic biologists. They were not looking for the thymus. The AI found it for them. The science that spent 30 years being ignored was correct. It took a machine looking at 25,000 scans without any prior assumptions to confirm what a small group of scientists had been saying for three decades. Sometimes the reason a field is underfunded is not that the question is unimportant. It is that the answer is inconvenient.

@DuaneStorey Whoever snuck onto their network knew enough to brute force a weak WPA key. I'm not surprised their MAC changes frequently. It's a client option in a few operating systems.

I found an intruder on my friend's WiFi network for years mostly streaming video. I suggested setting a stronger WPA3 passphrase. They are disturbed by the intrusion but decided changing the wifi password on a dozen devices is too much effort so just decided to let it happen.

@pjl788 They don't pay for their own home internet.

@DuaneStorey Randomized MAC address is pretty common these days.

If you have a weak WPA passphrase, neighbors can capture some raw packets and rent GPUs to brute force the secret. Many WiFi passphrases set by an ISP are too easy to brute force because it is something like a 10 digit number which GPUs can crack in seconds.

The idea vaccines cause autism was invented by Andrew Wakefield in 1998 and was so thoroughly debunked he lost his license for gross malpractice And here we are 27 years later RFK Jr dredging up the same nonsense Such a tiresome waste of time

MedCram reviewed Ivermectin for Covid in April of 2020 showing that Ivermectin prevented replication of SARS-CoV2 in vitro. But made it clear that this was only in a test tube! youtube.com/watch?v=nHzBLf… We later reviewed (2 years later) data in humans showing it didn't work. youtube.com/watch?v=nHzBLf… Since then numerous trials have confirmed this with different doses: Key U.S. trials: 1) ACTIV-6, ivermectin 400 µg/kg daily x 3 days — JAMA 2022 U.S. decentralized, double-blind, randomized placebo-controlled trial at 93 U.S. sites. Ivermectin did not significantly improve time to recovery, and hospitalization/death was essentially identical: 1.2% vs 1.2%. 2) ACTIV-6, higher-dose ivermectin up to 600 µg/kg daily x 6 days — JAMA 2023 Also U.S., double-blind, randomized, placebo-controlled. Median recovery was 11 days with ivermectin vs 12 days with placebo, but the posterior probability of reducing symptoms by more than 1 day was <0.1%, and urgent care/ED/hospitalization/death was 5.5% vs 5.8%. Authors concluded it did not support ivermectin use. 3) COVID-OUT — NEJM 2022 U.S. phase 3 randomized, double-blind, placebo-controlled factorial trial of metformin, ivermectin, and fluvoxamine. For ivermectin, the adjusted odds ratio for the primary composite outcome was 1.05, and for hospitalization/death was 0.73 with a very wide CI crossing 1; the trial concluded none of the three drugs prevented hypoxemia, ED visit, hospitalization, or death. The closest “positive” ivermectin signal in a rigorous recent community trial is not U.S. and not placebo-controlled: the UK PRINCIPLE trial was open-label and found a small symptom-duration signal, but the authors still said the findings did not support ivermectin use for COVID-19.