Patel Lab Oxford @LabPatel
Dr Smita Patel's Primary Immune Deficiency Lab at @UniofOxford expmedndm.ox.ac.uk/pi-dr-smita-pa… Oxford, England Joined June 2018-
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Immunodeficiency UK would like to say a huge THANK YOU to all the nurses, doctors and healthcare staff who care for people with immunodeficiency. We are so grateful for your hard work and dedication. Wishing all our NHS colleagues a Very Merry Christmas 🎄
If immunosuppressed this is for you 👇Not a moment to soon - access through a study for oral antiviral Molnupiravir. Any immunosuppressed patient over 18 or adult over 50 can enrol directly through this website if they test positive by PCR. panoramictrial.org
And of course thanks to the @OxfordBRC and @BritSocHaem for funding this work 🙏
With thanks to the patients and their families, the Clinical Immunology nursing team at OUH, the diagnostic lab team and our collaborators
How do we consider and evaluate polygenic causes of inborn errors of immunity? Our paper on a family with a known pathogenic mutation in NFKB1, a TNFRSF13B variant associated with CVID and a variant of interest in PIK3R1 in @ImmunologyNews authors.elsevier.com/a/1eG6l5P-5qOs…
Another excellent project from the immunology trainee network…. Dr Hadeil Morsi presents a short oral paper on a Muticentre UK based audit on acquired C1 inhibitor deficiency #UKPIN2021
Our pre-print [not yet peer reviewed] describing the outcomes following #SARSCoV2 infection in patients with primary and secondary immunodeficiency is now available to read online; large cohort (>300pt) with important messages for public health #COVID19 #immunodeficiency
Outcomes Following SARS-CoV-2 Infection in Patients With Primary and Secondary Immunodeficiency in The United Kingdom #covid researchsquare.com/article/rs-920…
sciencedirect.com/science/articl… Our updated chapter in Medicine: Infections in the immunocompromised host. with @LabPatel
Our recent paper, published in @JClinImmun, on the DNA damage response in #CVID highlighted by @nanostringtech 👇 and there’s more data to come! 🧬
#CVID is the most clinically prevalent cause of primary antibody failure. This week's #FridayRead comes from @ChantalH88 @LabPatel group @UniofOxford who used our #PlexSet to describe altered gene expression in DNA Repair for these patients. 📖 bit.ly/3xIQNks
And finally, we took primary cells from patients and controls, exposed them to gamma-irradiation, and measured key factors of the DNA damage response by flow cytometry. A striking finding in patients was decreased ATM in B cells correlating with increased apoptosis.
Delighted to share our research on the DNA damage response in CVID with our collaborators across Oxford, published this week in @JClinImmun.
Our paper @LabPatel exploring the DNA damage response and apoptosis in CVID is now online in @JClinImmun. With thanks to @sarah_sasson @arzii_x @anzilelo @jeg_cworth @KnightGenetics and others not on Twitter - Silvia, Liz and John Read it here 👇👇👇 link.springer.com/article/10.100…
SAVE THE DATE...... UKPIN 2021: Immune health through life and COVID will take place on 2-3 November at Cutlers' Hall, Sheffield. ukpin.org.uk/meetings/ukpin…
The winner of the IPOPI LeBien Award is Prof Helen Chapel! One of the IPOPI founders and long time supporters of patient involvement and patient centered care! Congratulations Prof Chapel #GPM2020 @ESIDsociety @INGID_Tweets
Delighted to see our case report published in @TheLancetRheum. Lifesaving extremely high dose intravenous anakinra reversed complete neurological unresponsiveness (CNS-HLH) in this child with severe cytokine storm (secondary-HLH/MAS). thelancet.com/journals/lanrh…
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