SickKids Cardiac Precision Medicine Program @SKCardPrecision
SickKids Cardiac Precision Medicine. Seeking to unravel the unique genome of every child with heart disease in an effort to deliver precision and timely care.cardiacprecisionmedicine.com Toronto, OntarioJoined November 2024
Drs @seema_mital, Joseph Rossano and Charles Canter shares insights on the SCOUT-HCM trial of mavacamten in adolescents at the @CCFheartkids (Children's Cardiomyopathy Foundation) webinar—advancing targeted therapies for pediatric HCM.
Watch here: youtube.com/watch?v=MGz7DT…
Check out the latest Heart Centre Biobank Participant Newsletter to see how samples & data are driving research forward 💙
A big thank you to our participants—your contributions are advancing discoveries and improving heart disease outcomes.
theheartcentrebiobank.com/wp-content/upl…
The global Phase 3 SCOUT‑HCM trial showed improved heart structure, function, and symptoms—without compromising heart pumping function. This is the first randomized Phase 3 trial of a disease‑targeted therapy in adolescents with obstructive HCM.
🌟 A major advance for children with heart disease 🌟
A landmark @NEJM study shows that mavacamten, a targeted cardiac therapy, can safely reduce dangerous heart obstruction in adolescents with obstructive HCM.
nejm.org/doi/full/10.10…
SickKids Leads: @JediJeewa@seema_mital
📣Trainees now attend FREE!
C4U 2026 is a one-day cardiovascular & critical care conference, now free for all trainees. Includes expanded Simulation Lab featuring ECMO, Impella, LVAD & more. Use code C4URESIDENT.
April 10 | Toronto
🔗 Register: c4uconference.com
A new study in @JACCJournals reveals a clear molecular signature behind diastolic dysfunction in children with cardiomyopathy, pointing to abnormal lipid signaling as a key driver.
Researchers also identified a potential blood-based lipid “fingerprint”
🔗 tedrogersresearch.ca/2026/02/abnorm…
Calling all cardiologists and trainees! Early bird registration for the C4U Clinical Cardiology and Critical Care Update Conference has been extended until Feb 15! Learn more and register today to sign up before rates go up 💸 c4uconference.com
🎉The 2026/27 TRCHR Education Fund is now accepting applications for projects supporting collaborative, heart failure–focused research across TRCHR partner institutions!
PhD Awards: $25,000
Post-Doc Awards: $40,000
Apply by March 30, 2026
tedrogersresearch.ca/education-fund/
New Publication in @GenomeMedicine:
“DNA methylation analysis of NOTCH1 variants reveals the first episignature for nonsyndromic CHD.”
✅Largest CHD cohort analyzed (3,907 cases)
✅ NOTCH1 = most frequent monogenic cause
✅ First DNAm episignature
link.springer.com/article/10.118…
Cardiac Precision Medicine in the 21st Century| October 29-31, 2025 | Toronto
We were thrilled to bring together leading experts, researchers, and clinicians—a multidisciplinary international community united by the goal: improving heart outcomes through precision medicine.
Thank you for joining us at the Intl. Cardiovascular Genomic Medicine & SickKids Cardiac Precision Medicine Conference! 🌍
We welcomed experts from 14 countries to explore #CardiacPrecisionMedicine in the age of Omics, AI & digital health.
📸 Highlights coming soon!
So exciting to see this presented by Dr. Frederick Roth at today’s Cardiac Precision Medicine Conference hosted by @SKCardPrecision, and now officially out!
Genomic variants in the LDL receptor are the big driver of atherosclerosis, but most were previously unclassified for their impact. Today @ScienceMagazine nearly all 17,000 variants (!) were assessed functionally, which markedly improves the diagnosis for familial high
Thrilled to have @EdgewiseTx join us in Toronto for the Cardiac Precision Medicine in the 21st Century Conference! Let’s advance the future of heart care together.
#CardiacPrecisionMed
We’ll be at the 10th International Cardiovascular Genomic Medicine & SickKids Cardiac Precision Medicine Conference in Toronto! We're proud to be a sponsor, bringing experts together to discuss cardiovascular genomics & precision medicine. @GenomFoundation@SKCardPrecision
⏳ Last chance to register! ⏳
Cardiac Precision Medicine in the 21st Century Conference
📅 Oct 29–31 | 📍 Toronto + Virtual
🔬 Genomics, Multi-Omics, AI, Precision Therapies & more
🎓 In person discounts for @trogersresearch: SickKids, UHN, U of T
🔗 cardiacprecisionmedicine.com
Join us at the Cardiac Precision Medicine in the 21st Century Conference for a special session sponsored by @illumina
🗓 Thurs. Oct 30 | 🕢 7:30 AM | 📍SickKids
🎙 Dr. David Lanfear
🧬 Making Precision More Practical: Design and Results of the CardioSeq Clinical Trial
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