Carlos Ronchi @chronchi
Mathematician. Computational Biologist. Newsletter: https://t.co/q3u5xgysOa chronchi.github.io Joined October 2015-
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New blog article challenging medical researchers who are drawn to clustering patients to create so-called "phenotypes" to think again: fharrell.com/post/cluster @MaartenvSmeden @statsepi0 #Statistics #PrecisionMedicine @vandy_biostat
I defended my PhD thesis at EPFL! Thank you everyone that joined and contributed in every aspect of my PhD. I'm looking forward to what comes next in Chicago!
Hearty congratulations, @chronchi on outstanding and engaging public thesis defense! Best of luck, and we look forward to seeing all the amazing things you will accomplish! @epflSV @nature_npj Learn more about EMBER: go.nature.com/3XYBTGA
Phenomenal work, tumor agnostic pipeline for oncology and precision medicine! ⬇️⬇️⬇️⬇️⬇️ @chronchi 's baby called #EMBER provides a calibration and reference tool that paves the way for using #RNAseq as a standard diagnostic and predictive tool for #ERpos breast cancer @CBrisken @epflSV #TCGA #METABRIC #SCANB #estrogen receptor signaling, cell #proliferation, #DNA repair, and #epithelial-mesenchymal #transition
I’m very happy to announce that our manuscript has been published at npj breast cancer, together with @CBrisken and Syed Haider! We propose a new algorithm to do single sample integration into a common reference space. (1/n) rdcu.be/dNeRN
@sflomos Definitely it's something that could be done, as ERBB2 and other genes on the HER2 amplicon region are in the list of >8000 genes for pathway analysis!
I’m very happy to announce that our manuscript has been published at npj breast cancer, together with @CBrisken and Syed Haider! We propose a new algorithm to do single sample integration into a common reference space. (1/n) rdcu.be/dNeRN
The analysis can be found online too (chronchi.github.io/molecular_land…) with all the figures and a chapter specific for the analysis done during the revision process. (6/6)
It was very important for us to make the study as reproducible as possible. I created a docker image in which everyone should be able to reproduce all the figures from the paper (github.com/chronchi/molec…). (5/n)
Don't like p-values? We're presenting a completely new interpretation in the context of clinical trials. With Andrew Gelman, Sander Greenland, @guido_imbens Simon Schwab and Steve Goodman. @Lester_Domes @goodmanmetrics @NEJMEvidence evidence.nejm.org/stoken/default…
Fantastic talk by @jcheng at #positconf2023 on using #shiny with #quartopub. I've made an #rstats Quarto book demo with a wasm-embedded shiny app to demonstrate how class boundaries change with the complexity of natural splines. Sources: github.com/topepo/shinyli…
It's amazing to see our work so beautifully represented, thank you @sciencebrush!
Polarons and bipolarons in crystalline and amrophous polymer domains. Excited to share this design 🎨 that I did for Prof. Natalie Banerji, first author Priscila Cavassin @CavassinP and colleagues from @DCBPunibern! The work was published in Advanced Materials @AdvSciNews and
In new work, @lambdamoses et al. introduce the Voyager platform for spatial and non-spatial 'omics analysis: 🚴♀️ Builds on the geospatial statistics tradition 🚴♀️ Addresses discordance between Seurat & Scanpy 🚴♀️ Engineered in R (@Bioconductor) & Python biorxiv.org/content/10.110… 1/🧵
🔊Scientists can now utilize an optimized preclinical model for lobular breast carcinoma, which accurately reflects the different cancer stages. This tool can help advance lobular breast research @epflSV @sflomos @CBrisken @brisken @MHH_life👏 📌Link here: mdpi.com/2072-6694/15/1…
Had a great time in Gent, both presenting and learning from the other ESRs and PIs!
Polarons and bipolarons in crystalline and amrophous polymer domains. Excited to share this design 🎨 that I did for Prof. Natalie Banerji, first author Priscila Cavassin @CavassinP and colleagues from @DCBPunibern! The work was published in Advanced Materials @AdvSciNews and
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