Joe Muldoon @JoeJMuldoon
Synthetic, systems, and computational immunologist. Cell therapy @UCSF San Francisco, CA Joined September 2019-
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Thrilled to report in @natBME our new effort to improve the manufacturing and access of gene edited T cells. Awesome collab with the @RossWilsonLab and @MarsonLab. We developed a protein-based delivery for CRISPR systems in human primary cells. A 🧵 by Ross 👇🏼
I’m excited to share our report - out now in @natBME - of a new approach to CRISPR delivery that is poised to transform the way engineered T cell therapies are manufactured. Visit tinyurl.com/CRISPR-PERC for “how to” details. It’s threadin’ time! (1/11) nature.com/articles/s4155…
I’m excited to share our report - out now in @natBME - of a new approach to CRISPR delivery that is poised to transform the way engineered T cell therapies are manufactured. Visit tinyurl.com/CRISPR-PERC for “how to” details. It’s threadin’ time! (1/11) nature.com/articles/s4155…
Thrilled to share the first Eyquem lab paper! Today we report in @CellCellPress evolving the AAV6 capsid to enable efficient engineering of murine T cells. An exciting collab with @asokanduke and led by the brilliants @WilliamNyberg and Jon Ark cell.com/cell/fulltext/… 🧵1/11
Excited to share our paper @CellCellPress tinyurl.com/22s9pztn. Ray Liu and Iowis Zhu led the development of clinically optimized and tunable nextgen synNotch receptors dubbed SNIPRs for cell therapies. Thank you @UCSF @GladstoneInst @parkerici press: tinyurl.com/2p8usz7z
Today we report in @NatureMedicine the HLA-independent TCR (HIT). Using CRISPR knockin, we remodeled the TCR specificity to target cell surface antigen in an HLA-Independent fashion and benefit from the TCR's unique sensitivity. 1/4 nature.com/articles/s4159…
Check out GAMES - a model development workflow for rigorous characterization of synthetic genetic systems! pubs.acs.org/doi/10.1021/ac…
Are you interested in using mathematical modeling to help understand, refine, or employ your synthetic biology system, but don’t know where to start? Introducing GAMES—a model development workflow for rigorous characterization of synthetic genetic systems.
Excited to share new work w/ co-lead @CamilliaAzimi, @MarsonLab @kickassscience1 @roybal_lab: using a method we call 'CAR Pooling', we tested many CARs in multiplex & found new non-T cell signaling domains which improve CAR-T efficacy. biorxiv.org/cgi/content/sh… 👇🧵 1/10
Very excited to be part of the Mnemo adventure and humbled to be a co-founder next to my former mentor Michel Sadelain, Isabelle Rivière and Sebastian Amigorena. endpts.com/michel-sadelai…
Thanks @NIBIBgov for highlighting this cool project led by @JoeJMuldoon with @BagheriLab @NUSynBio nibib.nih.gov/news-events/ne…
1/4 Excited to share our new preprint from the @roybal_lab & @MoKhalilLab-Raymond Liu and Iowis Zhu led the development of NextGen synNotch receptors. SynNotch is one ‘species’ in a larger ‘genus’ of SyNthetic Intramembrane Proteolysis Receptors (SNIPRs) tinyurl.com/7kf6bdyr
1/4 We’re excited to share two major papers out @ScienceTM showing the many benefits of synNotch CAR circuits for the treatment of solid tumors. Axel Hyrenius-Wittsten, an incredible postdoc @roybal_lab, led the studies in Ovarian Cancer and Mesothelioma. tinyurl.com/drje876u
Our new study on predictive design of mammalian genetic programs is out in @ScienceAdvances! We paired engineered genetic parts that have special capabilities with computational models to design circuits that perform sophisticated, useful functions advances.sciencemag.org/content/7/8/ea…
Nice piece on predictive design of mammalian genetic programs - a great collaboration with @BagheriLab led by @JoeJMuldoon. Beautiful art by Justin Muir. @NUSynBio @NIBIBgov @ScienceAdvances advances.sciencemag.org/content/7/8/ea… news.northwestern.edu/stories/2021/0…
Looking to obtain COMET or mMoClo plasmids from @Addgene ? We have deposited 291 plasmids and they are starting to become available on @TheLeonardLab Addgene Page. See thread below for more information and links:
Need a stocking stuffer? Our study on elucidating and refining synthetic receptor mechanisms is out in final version today @OUPSynBio! @NUSynBio @NorthwesternEng doi.org/10.1093/synbio…
A powerful approach for controlling delivery at the single cell level: this was a fun collaboration with @Espinosa_HDE, Jack Kessler, and teams @JoeJMuldoon @NUSynBio
Research Shows Cell Perturbation System Could Have Medical Applications | Northwestern Engineering mccormick.northwestern.edu/news/articles/…
Now on bioRxiv—we build upon and combine several mammalian syn bio technologies. Our approach enables the construction of a wide range of genetic programs, and it makes the leap from relying upon intuition to using accurate model-guided design. Very proud of the team.
Excited to share our new study on model-guided design of mammalian genetic programs! Using some new (and newish) synthetic genetic parts, we demonstrate predictive design of diverse, sophisticated functions @NUSynBio @NorthwesternEng biorxiv.org/content/10.110…
Congratulations @JoeJMuldoon (@TheLeonardLab and @BagheriLab) on your thesis seminar today! #IBiSGrads #IBiSAlumni
The Lucks Lab @LucksLab
3K Followers 341 Following The Julius B. Lucks Lab for RNA Engineering @NorthwesternU @NUSynBio
Josh Leonard @TheLeonardLab
2K Followers 441 Following News, Views, and Happenings. We're @NorthwesternU, @NuSynBio, @NorthwesternEng, @CLP_Institute. Opinions (and nearly all puns) are my own.
Adam Silverman @adsilverman627
1K Followers 1K Following Mainly interested in (cell-free) synthetic biology, diagnostics, and bad jokes, in roughly ascending order of significance
Justin Peruzzi @jperuzz
232 Followers 490 Following synthetic biologist interested in membrane biophysics & protein design | tech dev @ai_proteins | formerly @NUSynbio @NehaPKamat Lab, @UVAEngineers #gohoos
Kole Roybal @KoleRoybal
2K Followers 2K Following Immunologist/Synthetic Biologist @Roybal_Lab @UCSF, Director of UCSF @parkerici, Co-founder @ArsenalBio and Moonlight Bio, @Venrock
tyolabnu @tyolabnu
475 Followers 235 Following We use experimental and computational techniques to design biological systems for chemical synthesis and biosensing applications.
Katie Galloway @GallowayLabMIT
8K Followers 2K Following Assistant Prof @MITChemE ; mom^4 + wife; enjoys building cell-fate circuits, exploring dna topology, reprogramming the living world, and soccer; soli gloria deo
Rachel Rutishauser (m... @r_rutishauser
618 Followers 821 Following Physician-scientist, immunologist. Associate Prof @UCSF_EXPM, investigator @DAREtocureHIV. CD8 T cells, HIV, immune development. @rrutishauser.bsky.social
Kamat Lab @NehaPKamat
2K Followers 673 Following @kamatlab.bsky.social Associate Professor @NorthwesternU and a member of @NuSynBio Artificial cell design and membrane mechanobiology @NehaPKamat (Post)
Aditya Kunjapur @kunjapur
3K Followers 3K Following Thomas Willing Early Career Assoc. Prof. @UDelaware | Otto Mønsted Visiting Prof, DTU Fall '25 | Newer-to-nature building blocks #synbio https://t.co/4VVWd3IuKj
Leonardo Morsut @LeonardoMorsut
2K Followers 2K Following Synthetic developmental biologist that want to learn how to use nature’s masterpiece of embryonic development to build tissues - and run a healthy lab
Justin Eyquem @j_eyquem
2K Followers 501 Following Eyquem_Lab / Gene Editor and Synthetic Immunologist @UCSF. Investigator @GladstoneInst and @Parkerici
Juilliard Kate @JuilliardK52344
3 Followers 132 Following
Clara Kochendoerfer @Cmkochendoerfer
7 Followers 30 Following Biomedical Sciences PhD student at UCSF in the @roybal_lab
Lindsey Draper @Lindsey__Draper
356 Followers 581 Following Physician-scientist at @UCSF focusing on ovarian cancer. Engineering TIL in the @roybal_lab. @parkerici @MountSinaiNYC @theNCI
Adi Jangid @Adi_R_Jangid
123 Followers 329 Following bio fellow @8vc & phd student @roybal_lab engineering T cells to build therapeutics and program immunology
brewer briley💕 @brewer_briley
20 Followers 689 Following kinda people are my kind of people 💕💕 TIKTOK:brewer_briley
Clarity Chua @ClarityChua
12 Followers 89 Following
MstcZphr_71 @mstczphr92049
27 Followers 1K Following
Hersh Bhargava @HershBhargava
714 Followers 2K Following computational + synthetic biology → cell engineering // biophysics PhD candidate @UCSF (Lim & El-Samad Labs) // DoD NDSEG fellow // co-founder @skolayofficial
Bioengineering MDPI @Bioeng_MDPI
1K Followers 2K Following Bioengineering (ISSN 2306-5354, SCIE, IF 3.7) is an #openaccess journal on the science and technology of #bioengineering published by @MDPIopenaccess.
CANCER SUMMIT 2023 @DrugdiscoveryM
55 Followers 932 Following CANCER SUMMIT 2023 | December 14-15, 2023 Rome, Italy Venue: Mercure Roma West 🌐 https://t.co/Pecn6M5Ud5
Cancer Research Insti... @CancerResearch
31K Followers 5K Following Advancing cancer immunotherapy through research, collaboration and data-driven innovation. Creating a world #Immune2Cancer. Est. 1953.
Bradley Biggs @synbiobiggs
432 Followers 773 Following Incoming Assistant Prof. (Jan. 2025) Chemical Engineering at University of Michigan. Synthetic Biology & Metabolic Engineering.
Quentin Dudley @qmdudley
506 Followers 574 Following Assistant professor at UW-Madison @UWMadCBE working on plant and cell-free synthetic biology. Prev roadmapping a new biomanufacturing program for @Spec__Tech.
Zewen (Owen) Jiang, P... @OwenJ457
159 Followers 456 Following UCSF Graduate | Postdoc Researcher in Diet-Driven Immune Modulation, Inflammatory Diseases, and T Cell Biology.
Amaia Cadinanos-Garai @amaiacadi
55 Followers 437 Following Transforming scientific visions into life changing therapies. QC Specialist - USC/CHLA Cell Therapy Program
Aaron Morris @MorrisBioEng
503 Followers 328 Following I am a bioengineer focused on developing new tools to assess the immune system. Asst. Prof. of Biomedical Engineering at the University of Michigan
Max Mamonkin @MaxMamonkin
1K Followers 265 Following Engineering T cell therapies for cancer and chronic diseases | @Columbia Institute for Cell Engineering and Therapy (CICET)
María G @MgMorant
283 Followers 505 Following PhD. Scientist at @Integra_Tx. Geneticist and Biotechnologist specialized in Pharmaceutical Industry 🧬
Ry Leahy @RySciComms
833 Followers 3K Following Science Communications for Advanced Therapies - Cell & Gene Therapy - Rare Patient (EoE) #celltherapy #genetherapy #firstgenacademic
Sudip Subedi @the__biochemist
30 Followers 760 Following 𝐁𝐢𝐨𝐜𝐡𝐞𝐦𝐢𝐬𝐭 ~ Actively looking for a Ph.D. position & open to discussing opportunities in Genome Engineering, CRISPR, & NG Immuno-therapeutics.
Náurface von Dutchst... @Jrod527
294 Followers 1K Following known fan of Detroit-style pizza, Cate Blanchett, and Marisa Tomei
STEMCELL Technologies @STEMCELLTech
25K Followers 6K Following Committed to advancing life science research with innovative reagents, tools, and services. For product and technical support, email [email protected].
Prof. Truong-Son Hy @sonpascal93
559 Followers 6K Following Tenure-Track Assistant Professor at University of Alabama at Birmingham. Previous: Indiana State University, UC San Diego. PhD from University of Chicago.
dana foss @dv_foss
463 Followers 970 Following
Joe Sabatino @jsabatino37
1K Followers 865 Following MS Neurologist, T cell immunologist at @UCSF, Dept of Neurology, Weill Institute for Neurosciences. All posts are my own and not on behalf of UCSF
Daniel Hoces @DanielHoces
329 Followers 582 Following Postdoc @Stanford. Engineering immune cells to fight cancer. Ph.D. @ETH_en | M.D. @CayetanoHeredia 🇵🇪 🇨🇭
Ross Wilson @RossWilsonLab
919 Followers 165 Following CRISPR whisperer in perpetual training. We're working to enable safe & accessible delivery of genome editing therapeutics. @igisci @UCBerkeley https://t.co/89o53zRYUa
Charlotte Wang @HuiCharlotte
20 Followers 78 Following
walter navarro @walternavarro29
13 Followers 913 Following
Kira Downey @KiraKiraMD
205 Followers 450 Following Kira M. Downey. MD/PhD Student at @UCSFMedicine. Immune Engineering | Medicare for All | Oncology. https://t.co/YMHsB4tahQ
Vinod Kumar @vinodkumar_IITD
14 Followers 516 Following Doctoral Scholar, Control in systems and synthetic biology #RNAStructureModeling #BiomolecularCircuits #RnaThermometer #Riboswitch
Taylor Dolberg @TaylorDolberg
17 Followers 23 Following
Blaeschke Lab @FranziBlaeschke
326 Followers 219 Following News from Franzi Blaeschke's lab at the German Cancer Research Center (DKFZ) and Hopp Children's Cancer Center Heidelberg. Tweets represent personal views only.
Devin Stranford @DevinStranford
46 Followers 54 Following Scientist at @syenex. Interests: Synthetic biology, cell and gene therapies, engineering extracellular vesicles and enveloped vectors.
Biomed_Eng1987 @BiomedEng1987
488 Followers 5K Following I am a researcher with a very scientific curiosity to use new #biomaterials #biophysics in #regenerative medicine #cancer treatment #PRGF #TTFields.
Majo Duran @majo__duran
1K Followers 491 Following Costa Rican 🇨🇷 BE PhD Student @MIT. Previously @roybal_lab & @fiftyyears
Vivasvan Vykunta @VivaVykunta
97 Followers 127 Following MD-PhD Student @UCSF_MSTP with @MaxKrummel | Previously @MarsonLab @GladstoneInst and Zikherman Lab @UCSF | @PDSoros Fellow '26 | Immuno-engineering and biking
madeleine weinberg @weinberg_g
38 Followers 277 Following
Janvie Manhas @JanvieManhas
154 Followers 469 Following MD, PhD @ All India Institute of Medical Sciences, New Delhi | ICMR-DHR Young Scientist | SynBio | Genetic & Cellular engineering | Translational Medicine
Hyeong Ryeol Choi @HRChoi_CD247
26 Followers 114 Following Postdoc in UCSF, Interested in Immunotherapy
Talbot Alexis @DrAlexisTalbot
820 Followers 1K Following Assistant Professor in Immunology Paris #myeloma #MGCS #CART @aphp @HopSaintLouis @institut_IRSL @Univ_Paris @HIPI_inserm @UCSF https://t.co/Hfou5jiToD
@EPPIcenter at UCSF @EPPIcenter_UCSF
2K Followers 2K Following The EPPIcenter aims to advance the understanding of infectious diseases to reduce global morbidity and mortality. https://t.co/zp0NmGO1qg
The Lucks Lab @LucksLab
3K Followers 341 Following The Julius B. Lucks Lab for RNA Engineering @NorthwesternU @NUSynBio
Josh Leonard @TheLeonardLab
2K Followers 441 Following News, Views, and Happenings. We're @NorthwesternU, @NuSynBio, @NorthwesternEng, @CLP_Institute. Opinions (and nearly all puns) are my own.
Mo Khalil @MoKhalilLab
10K Followers 2K Following Prof. @ Harvard University, Broad Institute, and Wyss Institute. Understanding the natural world by building a synthetic one. website: https://t.co/PyjGQRHoUy
Adam Silverman @adsilverman627
1K Followers 1K Following Mainly interested in (cell-free) synthetic biology, diagnostics, and bad jokes, in roughly ascending order of significance
Justin Peruzzi @jperuzz
232 Followers 490 Following synthetic biologist interested in membrane biophysics & protein design | tech dev @ai_proteins | formerly @NUSynbio @NehaPKamat Lab, @UVAEngineers #gohoos
Tullman-Ercek Lab @DTELab
953 Followers 259 Following News from Danielle Tullman-Ercek's lab in Chemical and Biological Engineering and @NUSynBio at @northwesternU.
Kole Roybal @KoleRoybal
2K Followers 2K Following Immunologist/Synthetic Biologist @Roybal_Lab @UCSF, Director of UCSF @parkerici, Co-founder @ArsenalBio and Moonlight Bio, @Venrock
tyolabnu @tyolabnu
475 Followers 235 Following We use experimental and computational techniques to design biological systems for chemical synthesis and biosensing applications.
Rachel Rutishauser (m... @r_rutishauser
618 Followers 821 Following Physician-scientist, immunologist. Associate Prof @UCSF_EXPM, investigator @DAREtocureHIV. CD8 T cells, HIV, immune development. @rrutishauser.bsky.social
Kamat Lab @NehaPKamat
2K Followers 673 Following @kamatlab.bsky.social Associate Professor @NorthwesternU and a member of @NuSynBio Artificial cell design and membrane mechanobiology @NehaPKamat (Post)
Justin Eyquem @j_eyquem
2K Followers 501 Following Eyquem_Lab / Gene Editor and Synthetic Immunologist @UCSF. Investigator @GladstoneInst and @Parkerici
IBiS.northwestern @IBiSatNU
359 Followers 112 Following IBiS is the Interdisciplinary Biological Sciences PhD program at Northwestern.
Clara Kochendoerfer @Cmkochendoerfer
7 Followers 30 Following Biomedical Sciences PhD student at UCSF in the @roybal_lab
Lindsey Draper @Lindsey__Draper
356 Followers 581 Following Physician-scientist at @UCSF focusing on ovarian cancer. Engineering TIL in the @roybal_lab. @parkerici @MountSinaiNYC @theNCI
Adi Jangid @Adi_R_Jangid
123 Followers 329 Following bio fellow @8vc & phd student @roybal_lab engineering T cells to build therapeutics and program immunology
Clarity Chua @ClarityChua
12 Followers 89 Following
AD @researcherlizzy
60 Followers 0 Following
Hersh Bhargava @HershBhargava
714 Followers 2K Following computational + synthetic biology → cell engineering // biophysics PhD candidate @UCSF (Lim & El-Samad Labs) // DoD NDSEG fellow // co-founder @skolayofficial
Zewen (Owen) Jiang, P... @OwenJ457
159 Followers 456 Following UCSF Graduate | Postdoc Researcher in Diet-Driven Immune Modulation, Inflammatory Diseases, and T Cell Biology.
Max Mamonkin @MaxMamonkin
1K Followers 265 Following Engineering T cell therapies for cancer and chronic diseases | @Columbia Institute for Cell Engineering and Therapy (CICET)
dana foss @dv_foss
463 Followers 970 Following
Joe Sabatino @jsabatino37
1K Followers 865 Following MS Neurologist, T cell immunologist at @UCSF, Dept of Neurology, Weill Institute for Neurosciences. All posts are my own and not on behalf of UCSF
Charlotte Wang @HuiCharlotte
20 Followers 78 Following
Kira Downey @KiraKiraMD
205 Followers 450 Following Kira M. Downey. MD/PhD Student at @UCSFMedicine. Immune Engineering | Medicare for All | Oncology. https://t.co/YMHsB4tahQ
Ross Wilson @RossWilsonLab
919 Followers 165 Following CRISPR whisperer in perpetual training. We're working to enable safe & accessible delivery of genome editing therapeutics. @igisci @UCBerkeley https://t.co/89o53zRYUa
Josh Levy @josh_levy@... @josh__levy
354 Followers 445 Following Studying the links between biology and behavior. Flies+viruses. Currently Postdoc @scrippsresearch, PhD in Applied Math from @NorthwesternU
Blaeschke Lab @FranziBlaeschke
326 Followers 219 Following News from Franzi Blaeschke's lab at the German Cancer Research Center (DKFZ) and Hopp Children's Cancer Center Heidelberg. Tweets represent personal views only.
Devin Stranford @DevinStranford
46 Followers 54 Following Scientist at @syenex. Interests: Synthetic biology, cell and gene therapies, engineering extracellular vesicles and enveloped vectors.
Majo Duran @majo__duran
1K Followers 491 Following Costa Rican 🇨🇷 BE PhD Student @MIT. Previously @roybal_lab & @fiftyyears
Vivasvan Vykunta @VivaVykunta
97 Followers 127 Following MD-PhD Student @UCSF_MSTP with @MaxKrummel | Previously @MarsonLab @GladstoneInst and Zikherman Lab @UCSF | @PDSoros Fellow '26 | Immuno-engineering and biking
Mnemo Therapeutics @MnemoTx
199 Followers 34 Following
Talbot Alexis @DrAlexisTalbot
820 Followers 1K Following Assistant Professor in Immunology Paris #myeloma #MGCS #CART @aphp @HopSaintLouis @institut_IRSL @Univ_Paris @HIPI_inserm @UCSF https://t.co/Hfou5jiToD
Cell Design Institute... @CDI_UCSF
571 Followers 63 Following Official Account of the Cell Design Institute @UCSF. Bringing a unique foundational approach to cell therapies.
Zach Steinhart @CrisprEh
212 Followers 121 Following Postdoc in the @marsonlab @GladstoneInst/@UCSF. Parker Scholar @parkerici. Interested in genomics, CRISPR, cancer immunotherapy, and much more! 🇨🇦
Roybal Lab @roybal_lab
499 Followers 18 Following Updates from the Roybal Lab at UCSF. We are focused on engineering the next generation of immune cell therapeutics.
Taylor Gunnels @taylor_gunnels
89 Followers 607 Following Into making smarter medicines with synthetic biology. Recent Ph.D. grad | advised by @TheLeonardLab & @NehaPKamat | @NUSynBio
Xiaojing Gao @SynBioGaoLab
3K Followers 844 Following Assistant Professor @ Stanford ChemE synthetic biology, biomolecular engineering https://t.co/KAajKt7YdT
Kirsten Jaeyoung Jung @kirstenjung93
384 Followers 367 Following Scientist @mammothbiosci Engineering #RNA | ChemE PhD, Northwestern University | ChemE BS, Columbia University | @LucksLab @NuSynBio
Taylor Dolberg @TaylorDolberg
17 Followers 23 Following
Cellectis @cellectis
4K Followers 236 Following Cellectis is gene editing the first of its kind, off-the-shelf UCART immunotherapies to fight blood cancers. Community Guidelines: https://t.co/PpAC8G7hQp
ArsenalBio @ArsenalBio
2K Followers 65 Following We’re a programmable clinical-stage cell therapy company focused on the realization of solid tumor cell therapies. Our purpose is very clear: defeat cancer.
Daniel Bryan Goodman @dbgoodman
2K Followers 2K Following Immuno/Synth Bio/ML. PI @PennMedicine/@parkerici. Using DNA synth, multiplex assays & generative models to understand & engineer immune cells. @geochurch alum.
Yishan Chuang @YishanChuang
62 Followers 120 Following Systems biologist with a passion for personalized medicine. Believes strongly about the access to healthcare and education for everyone.
Anthony Kang @kanga_2roo
75 Followers 462 Following MD/MBA student @NUFeinbergMed/@KelloggSchool | synbio, tidyverse, taco tuesday
Bagheri Lab @BagheriLab
59 Followers 1 Following Modeling Dynamic Life Systems (MODYLS) Lab at Northwestern University
Katie Dreyer (she/her... @kdreyer96
81 Followers 224 Following Postdoctoral Scholar in the Moskowitz and Pott Labs at UChicago | Computational Biologist
ElowitzLab @ElowitzLab
12K Followers 1K Following Lab of Michael Elowitz at Caltech. Synthetic biology and systems biologyYou might like
