The Arany lab @AranyLab
We are the Arany lab at University of Pennsylvania. We love metabolism ! med.upenn.edu/aranylab/ University of Pennsylvania Joined December 2019-
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The Arany lab retweeted
New! Online now: Quantification of nutrient fluxes during acute exercise in mice dlvr.it/TFMr8Y
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Reporting with pride: (1) our star Jessie Axsom is now Dr.! (2) her paper is out @Cell_Metabolism: unbelievably comprehensive quantification of fuel fluxes in #exercise mice - lots of surprises. #MoTrPAC: take note. w/Rabinowitz lab. Free link 50days: authors.elsevier.com/a/1jxL75WXUlWk…
Fantastic brief historical overview of mechanism behind #preeclampsia from brilliant friend @ananthmsn34 in @jclinicalinvest : jci.org/articles/view/…
The Arany lab retweeted
From our newest anniversary focus issue on #Metabolism! "Human cardiac metabolism" @AranyLab @PennMedicine & colleagues Read the review: cell.com/cell-metabolis… #50YearsofCell
We think this one is groundbreaking: Do you wonder how #SGLT2 inhibitors protect from heart failure? We show that #empagliflozen directly activates PANK1, rate-limiting for CoA synthesis, in human hearts. You read it here first! biorxiv.org/content/10.110…
it's been a while since we posted... Here our recent review w/ @Rongtian2 on HUMAN cardiac metabolism in @Cell_Metabolism : deep dive going back 50+yrs - turned out to be >300 refs! Much is known, much MORE needs figured out... cell.com/cell-metabolis…
The Arany lab retweeted
CVI's Highlighted #PapersoftheWeek pubmed.ncbi.nlm.nih.gov/39041214/
Translating metabolic and cardiovascular research into effective treatments: What’s next? Some thoughts from several of us on the topic, in this issue of Cell: authors.elsevier.com/a/1jUX4L7PXqREY @JuleenRZierath @JolandavanderV4 @Alicardsdoc @rosenzweig_a @DebMuoio
@SeanM_Wu @IntMedAbel @UCLAHealth @AHAScience @BCVSearlyCareer @Joseph_C_Wu @Rongtian2 @RonglihL Appreciated the shoutouts, thank you Dale -- wonderful talk, as always!
The Arany lab retweeted
I am pleased to share a preprint ‘HIF2α-dependent inhibition of mitochondrial clustering of glutaminase suppresses clear cell renal cell carcinoma’. biorxiv.org/content/10.110…
A few days late: Congratulations to Daniel @daniel_baker_j for winning the 2024 @Phacilitate Young Scientist Award from Advanced Therapies Awards — including Glittering Gala dinner in Miami !
The Arany lab retweeted
New manuscript from our group studying DCM-TTNtvs and transcriptional modulators that reverse haploinsufficiency. ahajournals.org/doi/10.1161/CI…
The Arany lab retweeted
Interested in TTN/DCM? Check out current edition of @jclinicalinvest. 2 new reports: 1 by us w/ @Arany Lab and 1 from Miklos Kellermayer, plus commentary by @TravisHinson and Stuart Campbell. We know a lot more about TTN pathomechanisms! ...and we know what we don't know. 🧵1/4
14 key points from our recent review on peripartum cardiomyopathy #PPCM in @NEJM , summarized in @ACCinTouch , thank you @MelindaDavisMD. acc.org/Latest-in-Card…
The Arany lab retweeted
Review Article by Zoltan Arany, M.D., Ph.D. (@AranyLab): Peripartum Cardiomyopathy nej.md/48pUCx3 #Cardiology
Our latest review on peripartum cardiomyopathy #PPCM in @NEJM this week -- review of mechanism, genetics, clinical management, epi and prognosis -- lots of unknowns, huge racial disparities. Hope you enjoy it! nejm.org/doi/full/10.10…
The Arany lab retweeted
High fat consumption & blood pressure elevation ft. @BoaKim5, @WencaoZhao, Soon Tang, @MGLevin, @_AyonIbrahim, Yifan Yang, Ling Lai, Jian Li, @FitzGerald__Lab, @AranyLab (@PennCVI/ @PennIDOM) Emilia Roberts & Richard Assoian (@PennSysPharmATT) tinyurl.com/35b3tfm5
Cool: Lauren has just been selected to serve as the intern on the American Society of Nephrology Policy and Advocacy committee for Jan-Dec 2024 ! First non-postdoc/fellow that they’ve accepted, apparently! Congratulations !! @metabolauren @ASNKidney
Deadlines are approaching for @KeystoneSymp #Cardiometabolic Diseases: #EthnicDiversity in #PrecisionMedicine, this February in Vancouver! See scholarship, abstract and discount reg dates: keysym.us/KSCardiometab24 #KSCardiometab24 #Cardiovascular https://t.co/AlvAnX64WY
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